close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AOP35511.1Membrane protease subunit, stomatin/prohibitin; Derived by automated computational analysis using gene prediction method: Protein Homology. (340 aa)    
Predicted Functional Partners:
AOP35510.1
Sugar kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.954
hflB
Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
   
 0.906
AOP36623.1
NAD+ kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.778
AOP36003.1
AAA family ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.533
AOP35512.1
Fibronectin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.521
AOP35508.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.509
AOP35509.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.509
AOP32803.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0301 (AlgH) family.
   
    0.469
AOP35831.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.444
yidC
Preprotein translocase YidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.
  
 
 0.429
Your Current Organism:
Leptospira alstonii
NCBI taxonomy Id: 28452
Other names: ATCC BAA-2439, L. alstonii, Leptospira alstoni, Leptospira alstonii Smythe et al. 2013, Leptospira genomosp. 1, strain 79601
Server load: low (26%) [HD]