Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AOP35511.1Membrane protease subunit, stomatin/prohibitin; Derived by automated computational analysis using gene prediction method: Protein Homology. (340 aa)    
Predicted Functional Partners:
AOP35510.1
Sugar kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.955
coxB
Cytochrome C oxidase subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
   
 
 0.842
hflB
Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
   
 0.814
AOP36623.1
NAD+ kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.776
AOP33534.1
Peptidase M16; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.620
AOP34854.1
Peptidase M16; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.620
AOP34855.1
Zn-dependent peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase M16 family.
   
 0.620
AOP36318.1
Cation transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.583
AOP36003.1
AAA family ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.574
AOP32803.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0301 (AlgH) family.
   
    0.513
Your Current Organism:
Leptospira alstonii
NCBI taxonomy Id: 28452
Other names: ATCC BAA-2439, L. alstonii, Leptospira alstoni, Leptospira alstonii Smythe et al. 2013, Leptospira genomosp. 1, strain 79601
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