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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AOP35595.1HflC protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (260 aa)    
Predicted Functional Partners:
hflB
Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
   
 0.907
AOP35262.1
Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.621
AOP36003.1
AAA family ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.586
AOP35596.1
Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.513
AOP32803.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0301 (AlgH) family.
   
    0.481
AOP34855.1
Zn-dependent peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase M16 family.
 
 0.480
AOP34854.1
Peptidase M16; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.448
AOP34913.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.441
yidC
Preprotein translocase YidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.
  
 
 0.432
hflX
GTP-binding protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
  
  
 0.407
Your Current Organism:
Leptospira alstonii
NCBI taxonomy Id: 28452
Other names: ATCC BAA-2439, L. alstonii, Leptospira alstoni, Leptospira alstonii Smythe et al. 2013, Leptospira genomosp. 1, strain 79601
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