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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AOP35740.1AraC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (326 aa)    
Predicted Functional Partners:
AOP35741.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.589
AOP32474.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
 
 0.526
rpoD
RNA polymerase subunit sigma; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
   
 
 0.523
AOP33950.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
   0.503
AOP33202.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
   0.496
AOP33524.1
Dihydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.491
AOP32480.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   0.482
AOP33235.1
AraC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   0.461
AOP33150.1
DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   0.455
AOP36076.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.453
Your Current Organism:
Leptospira alstonii
NCBI taxonomy Id: 28452
Other names: ATCC BAA-2439, L. alstonii, Leptospira alstoni, Leptospira alstonii Smythe et al. 2013, Leptospira genomosp. 1, strain 79601
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