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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
flgLFlagellar biosynthesis protein FlgL; Derived by automated computational analysis using gene prediction method: Protein Homology. (421 aa)    
Predicted Functional Partners:
flgK
Flagellar biosynthesis protein FlgK; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.997
fliW
Flagellar assembly protein FliW; Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
 
 
 0.996
fliD
Flagellar hook protein FliD; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
 
 
 0.991
flgB
Flagellar biosynthesis protein FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
 
 
 0.990
fliM
Flagellar motor switch protein FliM; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
 
  
 0.988
fliE
Flagellar hook-basal body protein FliE; Forms a junction between the M-ring and FlgB during the flagella biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.987
fliF
Flagellar M-ring protein FliF; The M ring may be actively involved in energy transduction. Belongs to the FliF family.
 
  
 0.984
fliS
Flagellar export chaperone FliS; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.983
fliH
Flagellar assembly protein FliH; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.981
fliL
Endoflagellar basal body-associated protein; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.
 
  
 0.976
Your Current Organism:
Leptospira alstonii
NCBI taxonomy Id: 28452
Other names: ATCC BAA-2439, L. alstonii, Leptospira alstoni, Leptospira alstonii Smythe et al. 2013, Leptospira genomosp. 1, strain 79601
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