Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AOP36453.1HD family phosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (283 aa)    
Predicted Functional Partners:
aroK
Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
       0.845
cheD-2
Chemotaxis protein CheD; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.
       0.845
AOP36455.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.773
AOP36456.1
Pheromone shutdown protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.697
AOP36457.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.686
flgI
Flagellar biosynthesis protein FlgI; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
 
     0.667
AOP36458.1
Penicillin-binding protein activator LpoB; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.632
flgG
Flagellar basal-body rod protein FlgG; Makes up the distal portion of the flagellar basal body rod; Bradyrhizobium has one thick flagellum and several thin flagella; the Bradyrhizobium protein in this cluster is associated with the thick flagella; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.535
AOP32934.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 
 0.517
AOP36451.1
Recombinase XerD; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 'phage' integrase family.
       0.513
Your Current Organism:
Leptospira alstonii
NCBI taxonomy Id: 28452
Other names: ATCC BAA-2439, L. alstonii, Leptospira alstoni, Leptospira alstonii Smythe et al. 2013, Leptospira genomosp. 1, strain 79601
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