node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDF80766.1 | SDF84609.1 | SAMN05216571_10296 | SAMN05216571_102275 | Glutamate synthase (NADPH/NADH) large chain. | 2,4-dienoyl-CoA reductase. | 0.999 |
SDF80766.1 | SDF84630.1 | SAMN05216571_10296 | SAMN05216571_102276 | Glutamate synthase (NADPH/NADH) large chain. | L-threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. | 0.552 |
SDF80766.1 | SDF86344.1 | SAMN05216571_10296 | SAMN05216571_102357 | Glutamate synthase (NADPH/NADH) large chain. | Sarcosine oxidase subunit delta. | 0.959 |
SDF80766.1 | SDF86366.1 | SAMN05216571_10296 | SAMN05216571_102358 | Glutamate synthase (NADPH/NADH) large chain. | Sarcosine oxidase subunit alpha; Belongs to the GcvT family. | 0.975 |
SDF80766.1 | SDG58064.1 | SAMN05216571_10296 | SAMN05216571_12140 | Glutamate synthase (NADPH/NADH) large chain. | L-threonine synthase. | 0.754 |
SDF80766.1 | gcvP | SAMN05216571_10296 | SAMN05216571_103272 | Glutamate synthase (NADPH/NADH) large chain. | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.959 |
SDF80766.1 | glyA | SAMN05216571_10296 | SAMN05216571_101142 | Glutamate synthase (NADPH/NADH) large chain. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.921 |
SDF80766.1 | glyA-2 | SAMN05216571_10296 | SAMN05216571_102355 | Glutamate synthase (NADPH/NADH) large chain. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.921 |
SDF80766.1 | ilvA | SAMN05216571_10296 | SAMN05216571_105115 | Glutamate synthase (NADPH/NADH) large chain. | L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.637 |
SDF84609.1 | SDF80766.1 | SAMN05216571_102275 | SAMN05216571_10296 | 2,4-dienoyl-CoA reductase. | Glutamate synthase (NADPH/NADH) large chain. | 0.999 |
SDF84609.1 | SDF84630.1 | SAMN05216571_102275 | SAMN05216571_102276 | 2,4-dienoyl-CoA reductase. | L-threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. | 0.641 |
SDF84609.1 | SDF86366.1 | SAMN05216571_102275 | SAMN05216571_102358 | 2,4-dienoyl-CoA reductase. | Sarcosine oxidase subunit alpha; Belongs to the GcvT family. | 0.778 |
SDF84609.1 | gcvP | SAMN05216571_102275 | SAMN05216571_103272 | 2,4-dienoyl-CoA reductase. | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.824 |
SDF84630.1 | SDF80766.1 | SAMN05216571_102276 | SAMN05216571_10296 | L-threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. | Glutamate synthase (NADPH/NADH) large chain. | 0.552 |
SDF84630.1 | SDF84609.1 | SAMN05216571_102276 | SAMN05216571_102275 | L-threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. | 2,4-dienoyl-CoA reductase. | 0.641 |
SDF84630.1 | SDF86344.1 | SAMN05216571_102276 | SAMN05216571_102357 | L-threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. | Sarcosine oxidase subunit delta. | 0.895 |
SDF84630.1 | SDF86366.1 | SAMN05216571_102276 | SAMN05216571_102358 | L-threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. | Sarcosine oxidase subunit alpha; Belongs to the GcvT family. | 0.872 |
SDF84630.1 | SDG58064.1 | SAMN05216571_102276 | SAMN05216571_12140 | L-threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. | L-threonine synthase. | 0.939 |
SDF84630.1 | bioF | SAMN05216571_102276 | SAMN05216571_1129 | L-threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.769 |
SDF84630.1 | gcvP | SAMN05216571_102276 | SAMN05216571_103272 | L-threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.962 |