| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KOO37184.1 | queC | AMD01_22130 | AMD01_01810 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). | 0.601 |
| KOO46047.1 | KOO50510.1 | AMD01_09210 | AMD01_01815 | Anaerobic sulfatase maturase; anSME; radical SAM enzyme; oxidizes both cysteine and serine residues to C-alpha-formylglycine in sulfatase enzyme protein substrates; Derived by automated computational analysis using gene prediction method: Protein Homology. | 6-carboxy-5,6,7,8-tetrahydropterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.464 |
| KOO46047.1 | queC | AMD01_09210 | AMD01_01810 | Anaerobic sulfatase maturase; anSME; radical SAM enzyme; oxidizes both cysteine and serine residues to C-alpha-formylglycine in sulfatase enzyme protein substrates; Derived by automated computational analysis using gene prediction method: Protein Homology. | 7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). | 0.459 |
| KOO46047.1 | queE | AMD01_09210 | AMD01_01820 | Anaerobic sulfatase maturase; anSME; radical SAM enzyme; oxidizes both cysteine and serine residues to C-alpha-formylglycine in sulfatase enzyme protein substrates; Derived by automated computational analysis using gene prediction method: Protein Homology. | 7-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.456 |
| KOO50510.1 | KOO46047.1 | AMD01_01815 | AMD01_09210 | 6-carboxy-5,6,7,8-tetrahydropterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Anaerobic sulfatase maturase; anSME; radical SAM enzyme; oxidizes both cysteine and serine residues to C-alpha-formylglycine in sulfatase enzyme protein substrates; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.464 |
| KOO50510.1 | KOO50513.1 | AMD01_01815 | AMD01_01830 | 6-carboxy-5,6,7,8-tetrahydropterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.455 |
| KOO50510.1 | queC | AMD01_01815 | AMD01_01810 | 6-carboxy-5,6,7,8-tetrahydropterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). | 0.988 |
| KOO50510.1 | queE | AMD01_01815 | AMD01_01820 | 6-carboxy-5,6,7,8-tetrahydropterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 7-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.998 |
| KOO50510.1 | queF | AMD01_01815 | AMD01_01825 | 6-carboxy-5,6,7,8-tetrahydropterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.940 |
| KOO50513.1 | KOO50510.1 | AMD01_01830 | AMD01_01815 | Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 6-carboxy-5,6,7,8-tetrahydropterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.455 |
| KOO50513.1 | queC | AMD01_01830 | AMD01_01810 | Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). | 0.455 |
| KOO50513.1 | queE | AMD01_01830 | AMD01_01820 | Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 7-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.455 |
| KOO50513.1 | queF | AMD01_01830 | AMD01_01825 | Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.640 |
| glmS | murD | AMD01_21275 | AMD01_20755 | Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.414 |
| glmS | queC | AMD01_21275 | AMD01_01810 | Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). | 0.614 |
| glmS | queE | AMD01_21275 | AMD01_01820 | Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 7-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.671 |
| murD | glmS | AMD01_20755 | AMD01_21275 | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.414 |
| murD | queC | AMD01_20755 | AMD01_01810 | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). | 0.644 |
| queC | KOO37184.1 | AMD01_01810 | AMD01_22130 | 7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.601 |
| queC | KOO46047.1 | AMD01_01810 | AMD01_09210 | 7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). | Anaerobic sulfatase maturase; anSME; radical SAM enzyme; oxidizes both cysteine and serine residues to C-alpha-formylglycine in sulfatase enzyme protein substrates; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.459 |