| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KOO42995.1 | KOO46539.1 | AMD01_17850 | AMD01_12010 | NADPH--cytochrome reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; In the N-terminal section; belongs to the cytochrome P450 family. | uroporphyrin-III methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.540 |
| KOO42995.1 | KOO46551.1 | AMD01_17850 | AMD01_12070 | NADPH--cytochrome reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; In the N-terminal section; belongs to the cytochrome P450 family. | cobalt-precorrin-3B C(17)-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.967 |
| KOO42995.1 | KOO48541.1 | AMD01_17850 | AMD01_04755 | NADPH--cytochrome reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; In the N-terminal section; belongs to the cytochrome P450 family. | uroporphyrin-III methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.540 |
| KOO42995.1 | KOO50864.1 | AMD01_17850 | AMD01_03785 | NADPH--cytochrome reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; In the N-terminal section; belongs to the cytochrome P450 family. | FAD-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.429 |
| KOO42995.1 | cysC | AMD01_17850 | AMD01_04750 | NADPH--cytochrome reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; In the N-terminal section; belongs to the cytochrome P450 family. | Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. | 0.933 |
| KOO42995.1 | cysH | AMD01_17850 | AMD01_04740 | NADPH--cytochrome reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; In the N-terminal section; belongs to the cytochrome P450 family. | Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. | 0.954 |
| KOO42995.1 | cysI | AMD01_17850 | AMD01_19865 | NADPH--cytochrome reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; In the N-terminal section; belongs to the cytochrome P450 family. | Sulfite reductase; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.983 |
| KOO42995.1 | sat | AMD01_17850 | AMD01_04745 | NADPH--cytochrome reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; In the N-terminal section; belongs to the cytochrome P450 family. | ATP sulfurylase; ATPS; converts ATP and sulfate to 5'phosphosulfate and pyrophosphate; in some organisms this enzyme is involved in the incorporation of inorganic sulfate while in others it is involved in the production of ATP in the reverse direction; the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.871 |
| KOO42995.1 | sdhA | AMD01_17850 | AMD01_08235 | NADPH--cytochrome reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; In the N-terminal section; belongs to the cytochrome P450 family. | Part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.429 |
| KOO46539.1 | KOO42995.1 | AMD01_12010 | AMD01_17850 | uroporphyrin-III methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | NADPH--cytochrome reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; In the N-terminal section; belongs to the cytochrome P450 family. | 0.540 |
| KOO46539.1 | KOO46551.1 | AMD01_12010 | AMD01_12070 | uroporphyrin-III methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | cobalt-precorrin-3B C(17)-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.984 |
| KOO46539.1 | KOO48541.1 | AMD01_12010 | AMD01_04755 | uroporphyrin-III methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | uroporphyrin-III methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.512 |
| KOO46539.1 | KOO48542.1 | AMD01_12010 | AMD01_04765 | uroporphyrin-III methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.969 |
| KOO46539.1 | cysC | AMD01_12010 | AMD01_04750 | uroporphyrin-III methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. | 0.708 |
| KOO46539.1 | cysH | AMD01_12010 | AMD01_04740 | uroporphyrin-III methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. | 0.879 |
| KOO46539.1 | cysI | AMD01_12010 | AMD01_19865 | uroporphyrin-III methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | Sulfite reductase; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.829 |
| KOO46539.1 | sat | AMD01_12010 | AMD01_04745 | uroporphyrin-III methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP sulfurylase; ATPS; converts ATP and sulfate to 5'phosphosulfate and pyrophosphate; in some organisms this enzyme is involved in the incorporation of inorganic sulfate while in others it is involved in the production of ATP in the reverse direction; the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.703 |
| KOO46551.1 | KOO42995.1 | AMD01_12070 | AMD01_17850 | cobalt-precorrin-3B C(17)-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | NADPH--cytochrome reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; In the N-terminal section; belongs to the cytochrome P450 family. | 0.967 |
| KOO46551.1 | KOO46539.1 | AMD01_12070 | AMD01_12010 | cobalt-precorrin-3B C(17)-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | uroporphyrin-III methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.984 |
| KOO46551.1 | KOO48541.1 | AMD01_12070 | AMD01_04755 | cobalt-precorrin-3B C(17)-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | uroporphyrin-III methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.949 |