| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KOO37099.1 | KOO47698.1 | AMD01_21665 | AMD01_05725 | O-acetylhomoserine aminocarboxypropyltransferase; Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; Derived by automated computational analysis using gene prediction method: Protein Homology. | CoA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.779 |
| KOO37099.1 | KOO48492.1 | AMD01_21665 | AMD01_04490 | O-acetylhomoserine aminocarboxypropyltransferase; Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; Derived by automated computational analysis using gene prediction method: Protein Homology. | Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.902 |
| KOO37099.1 | KOO50533.1 | AMD01_21665 | AMD01_01930 | O-acetylhomoserine aminocarboxypropyltransferase; Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.939 |
| KOO37099.1 | KOO50534.1 | AMD01_21665 | AMD01_01935 | O-acetylhomoserine aminocarboxypropyltransferase; Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; Derived by automated computational analysis using gene prediction method: Protein Homology. | Homocysteine methyltransferase; Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine; expressed in B. subtilis under methionine starvation conditions; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.878 |
| KOO37099.1 | ilvA | AMD01_21665 | AMD01_03390 | O-acetylhomoserine aminocarboxypropyltransferase; Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; Derived by automated computational analysis using gene prediction method: Protein Homology. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.624 |
| KOO37099.1 | luxS | AMD01_21665 | AMD01_07450 | O-acetylhomoserine aminocarboxypropyltransferase; Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; Derived by automated computational analysis using gene prediction method: Protein Homology. | S-ribosylhomocysteinase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | 0.640 |
| KOO37099.1 | metAA | AMD01_21665 | AMD01_03290 | O-acetylhomoserine aminocarboxypropyltransferase; Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; Derived by automated computational analysis using gene prediction method: Protein Homology. | Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. | 0.962 |
| KOO41040.1 | KOO47698.1 | AMD01_18970 | AMD01_05725 | Fur family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Fur family. | CoA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.719 |
| KOO43898.1 | KOO47698.1 | AMD01_14260 | AMD01_05725 | Fur family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Fur family. | CoA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.530 |
| KOO46187.1 | KOO47698.1 | AMD01_10000 | AMD01_05725 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | CoA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.530 |
| KOO47698.1 | KOO37099.1 | AMD01_05725 | AMD01_21665 | CoA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | O-acetylhomoserine aminocarboxypropyltransferase; Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.779 |
| KOO47698.1 | KOO41040.1 | AMD01_05725 | AMD01_18970 | CoA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Fur family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Fur family. | 0.719 |
| KOO47698.1 | KOO43898.1 | AMD01_05725 | AMD01_14260 | CoA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Fur family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Fur family. | 0.530 |
| KOO47698.1 | KOO46187.1 | AMD01_05725 | AMD01_10000 | CoA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.530 |
| KOO47698.1 | KOO48492.1 | AMD01_05725 | AMD01_04490 | CoA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.750 |
| KOO47698.1 | KOO50533.1 | AMD01_05725 | AMD01_01930 | CoA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.738 |
| KOO47698.1 | KOO50534.1 | AMD01_05725 | AMD01_01935 | CoA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Homocysteine methyltransferase; Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine; expressed in B. subtilis under methionine starvation conditions; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.747 |
| KOO47698.1 | ilvA | AMD01_05725 | AMD01_03390 | CoA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.665 |
| KOO47698.1 | luxS | AMD01_05725 | AMD01_07450 | CoA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | S-ribosylhomocysteinase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | 0.659 |
| KOO47698.1 | metAA | AMD01_05725 | AMD01_03290 | CoA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. | 0.612 |