STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rbsK-2Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (307 aa)    
Predicted Functional Partners:
KOO41182.1
Deoxyribose mutarotase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.930
rbsD
Ribose ABC transporter; Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
 
  
 0.908
KOO42940.1
PTS fructose transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.860
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
 
 0.850
KOO41183.1
Sugar:proton symporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.831
rbsC
Ribose ABC transporter permease; Functions to transport ribose at high affinity; forms a complex with RbsA2C2B; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family.
 
  
 0.815
KOO50432.1
Mannose-1-phosphate guanylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.810
KOO42936.1
Nucleoside hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.804
guaB
Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 
 0.779
deoC-2
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
  
 0.767
Your Current Organism:
Bacillus koreensis
NCBI taxonomy Id: 284581
Other names: B. koreensis, Bacillus koreensis Lim et al. 2006, Bacillus sp. BR030, DSM 16467, KCTC 3914, strain BR030
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