STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EGD2Nascent polypeptide-associated complex subunit alpha; Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of th [...] (176 aa)    
Predicted Functional Partners:
EGD1
Nascent polypeptide-associated complex subunit beta; Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the [...]
   
 
 0.999
KLLA0_E22001g
60S ribosomal protein L13; Belongs to the eukaryotic ribosomal protein eL13 family.
   
   0.968
KLLA0_A06336g
KLLA0A06336p; Belongs to the universal ribosomal protein uL22 family.
   
 
 0.967
KLLA0_D05643g
KLLA0D05643p.
  
   0.956
KLLA0_E00573g
KLLA0E00573p.
   
   0.954
KLLA0_B13409g
KLLA0B13409p.
 
 
   0.950
KLLA0_F08657g
60S ribosomal protein L20; Belongs to the eukaryotic ribosomal protein eL20 family.
   
   0.943
RPS1
40S ribosomal protein S1; Belongs to the eukaryotic ribosomal protein eS1 family.
   
 
 0.941
KLLA0_D06941g
KLLA0D06941p.
   
 
 0.940
KLLA0_A07227g
KLLA0A07227p.
   
 
 0.940
Your Current Organism:
Kluyveromyces lactis
NCBI taxonomy Id: 284590
Other names: K. lactis NRRL Y-1140, Kluyveromyces lactis NRRL Y-1140
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