STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECO1N-acetyltransferase ECO1; Probable acetyltransferase required for the establishment of sister chromatid cohesion and couple the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together. In contrast to the structural cohesins, the deposition and establishment factors are required only during S phase. Acts by acetylating the cohesin complex component SMC3 (By similarity). (271 aa)    
Predicted Functional Partners:
KLLA0_A00286g
Structural maintenance of chromosomes protein.
   
 0.991
KLLA0_F25806g
KLLA0F25806p.
   
 0.947
KLLA0_F14795g
KLLA0F14795p.
   
 0.898
KLLA0_D07502g
Structural maintenance of chromosomes protein.
   
 0.884
KLLA0_F27797g
KLLA0F27797p.
   
 0.852
KLLA0_B07084g
KLLA0B07084p.
    
 
 0.834
KLLA0_F19085g
Structural maintenance of chromosomes protein.
   
 0.831
KLLA0_B12078g
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.829
KLLA0_A02981g
KLLA0A02981p.
   
 0.820
KLLA0_F07997g
KLLA0F07997p.
   
 0.785
Your Current Organism:
Kluyveromyces lactis
NCBI taxonomy Id: 284590
Other names: K. lactis NRRL Y-1140, Kluyveromyces lactis NRRL Y-1140
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