STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
URA9Dihydroorotate dehydrogenase (quinone), mitochondrial; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (445 aa)    
Predicted Functional Partners:
KLLA0_D02926g
KLLA0D02926p.
  
 
 0.989
URA5
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP); Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
  
 0.987
KLLA0_A09801g
KLLA0A09801p.
  
 
 0.931
URA1
Dihydroorotate dehydrogenase (fumarate); Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor.
     
0.929
URA3
Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family.
  
 0.910
KLLA0_C19107g
KLLA0C19107p.
  
 0.828
KLLA0_C04301g
KLLA0C04301p.
  
 0.826
KLLA0_E02531g
NADPH:adrenodoxin oxidoreductase, mitochondrial.
  
 0.817
GUA1
GMP synthase [glutamine-hydrolyzing].
  
 0.788
CBR1
NADH-cytochrome b5 reductase 1; Electron donor reductase for cytochrome b5. The cytochrome b5/NADH cytochrome b5 reductase electron transfer system supports the catalytic activity of several sterol biosynthetic enzymes (By similarity).
  
 0.762
Your Current Organism:
Kluyveromyces lactis
NCBI taxonomy Id: 284590
Other names: K. lactis NRRL Y-1140, Kluyveromyces lactis NRRL Y-1140
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