STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAF17Putative transferase CAF17, mitochondrial. (462 aa)    
Predicted Functional Partners:
KLLA0_B06754g
Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.
     
 0.771
KLLA0_A03597g
Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family.
     
 0.757
KLLA0_D07458g
KLLA0D07458p; Belongs to the dihydrofolate reductase family.
   
 
 0.755
KLLA0_B09504g
KLLA0B09504p.
  
 
 0.722
KLLA0_A07953g
KLLA0A07953p.
     
 0.700
KLLA0_D12738g
Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine.
     
 0.697
KLLA0_F18150g
KLLA0F18150p.
  
 
 0.688
DAD4
DASH complex subunit DAD4; Component of the DASH complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. The DASH complex mediates the formation and maintenance of bipolar kinetochore-microtubule attachments by forming closed rings around spindle microtubules and establishing interactions with proteins from the central kinetochore (By similarity).
     
 0.687
KLLA0_F08921g
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
    
 0.672
SHM1
Serine hydroxymethyltransferase, mitochondrial; Interconversion of serine and glycine.
    
 0.672
Your Current Organism:
Kluyveromyces lactis
NCBI taxonomy Id: 284590
Other names: K. lactis NRRL Y-1140, Kluyveromyces lactis NRRL Y-1140
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.