node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KLLA0_A08844g | KLLA0_C01628g | Q6CXF1 | Q6CUX1 | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. | KLLA0C01628p. | 0.654 |
KLLA0_A08844g | KLLA0_D12694g | Q6CXF1 | Q6CR11 | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. | KLLA0D12694p. | 0.992 |
KLLA0_A08844g | KLLA0_E07371g | Q6CXF1 | B4UN92 | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. | KLLA0E07371p. | 0.999 |
KLLA0_A08844g | KLLA0_E20241g | Q6CXF1 | Q6CMH2 | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. | DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. | 0.972 |
KLLA0_A08844g | LIG4 | Q6CXF1 | Q6CSH0 | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. | DNA ligase 4; Involved in ds DNA break repair. Has a role in non-homologous integration (NHI) pathways where it is required in the final step of non-homologous end-joining; Belongs to the ATP-dependent DNA ligase family. | 0.689 |
KLLA0_A08844g | MEC1 | Q6CXF1 | Q6CT34 | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. | Serine/threonine-protein kinase MEC1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Recruited to DNA lesions in order to initiate the DNA repair by homologous recombination. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, also involved in the regulation of DNA damage response mechanism. Required for cell growth and meiotic recombina [...] | 0.959 |
KLLA0_A08844g | MUS81 | Q6CXF1 | Q6CPQ8 | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. | Crossover junction endonuclease MUS81; Interacts with EME1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single- end invasion (SEI) (By similarity); Belongs to the XPF family. | 0.883 |
KLLA0_A08844g | RAD52 | Q6CXF1 | P41768 | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. | DNA repair and recombination protein RAD52; Involved in DNA double-strand break (DSB) repair and recombination. Promotes the annealing of complementary single-stranded DNA and by stimulation of the RAD51 recombinase (By similarity). | 0.997 |
KLLA0_A08844g | RAD59 | Q6CXF1 | Q9HEU2 | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. | DNA repair protein RAD59; Involved in the repair of double-strand breaks in DNA during vegetative growth via recombination and single-strand annealing. Anneals complementary single-stranded DNA (By similarity). | 0.898 |
KLLA0_C01628g | KLLA0_A08844g | Q6CUX1 | Q6CXF1 | KLLA0C01628p. | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. | 0.654 |
KLLA0_C01628g | KLLA0_D12694g | Q6CUX1 | Q6CR11 | KLLA0C01628p. | KLLA0D12694p. | 0.878 |
KLLA0_C01628g | KLLA0_E05039g | Q6CUX1 | Q6CPG7 | KLLA0C01628p. | KLLA0E05039p; Belongs to the ubiquitin-conjugating enzyme family. | 0.999 |
KLLA0_C01628g | KLLA0_E07371g | Q6CUX1 | B4UN92 | KLLA0C01628p. | KLLA0E07371p. | 0.590 |
KLLA0_C01628g | KLLA0_E20241g | Q6CUX1 | Q6CMH2 | KLLA0C01628p. | DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. | 0.657 |
KLLA0_C01628g | MUS81 | Q6CUX1 | Q6CPQ8 | KLLA0C01628p. | Crossover junction endonuclease MUS81; Interacts with EME1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single- end invasion (SEI) (By similarity); Belongs to the XPF family. | 0.548 |
KLLA0_C01628g | RAD52 | Q6CUX1 | P41768 | KLLA0C01628p. | DNA repair and recombination protein RAD52; Involved in DNA double-strand break (DSB) repair and recombination. Promotes the annealing of complementary single-stranded DNA and by stimulation of the RAD51 recombinase (By similarity). | 0.832 |
KLLA0_C01628g | RAD59 | Q6CUX1 | Q9HEU2 | KLLA0C01628p. | DNA repair protein RAD59; Involved in the repair of double-strand breaks in DNA during vegetative growth via recombination and single-strand annealing. Anneals complementary single-stranded DNA (By similarity). | 0.765 |
KLLA0_D12694g | KLLA0_A08844g | Q6CR11 | Q6CXF1 | KLLA0D12694p. | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. | 0.992 |
KLLA0_D12694g | KLLA0_C01628g | Q6CR11 | Q6CUX1 | KLLA0D12694p. | KLLA0C01628p. | 0.878 |
KLLA0_D12694g | KLLA0_E05039g | Q6CR11 | Q6CPG7 | KLLA0D12694p. | KLLA0E05039p; Belongs to the ubiquitin-conjugating enzyme family. | 0.807 |