STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACH1Acetyl-CoA hydrolase; Presumably involved in regulating the intracellular acetyl- CoA pool for fatty acid and cholesterol synthesis and fatty acid oxidation. (523 aa)    
Predicted Functional Partners:
ACS2
Acetyl-coenzyme A synthetase 2.
  
 0.964
KLLA0_F23914g
Malate synthase; Belongs to the malate synthase family.
   
 
 0.958
ACS1
Acetyl-coenzyme A synthetase 1; May be required for assimilation of ethanol and acetate.
  
 0.953
KLLA0_D12056g
KLLA0D12056p; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.952
KLLA0_A05478g
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
   
 0.932
KLLA0_F00440g
KLLA0F00440p; Belongs to the aldehyde dehydrogenase family.
  
 
 0.930
KLLA0_E23057g
KLLA0E23057p; Belongs to the aldehyde dehydrogenase family.
  
 
 0.930
KLLA0_D10021g
KLLA0D10021p; Belongs to the aldehyde dehydrogenase family.
  
 
 0.930
KLLA0_D09999g
KLLA0D09999p; Belongs to the aldehyde dehydrogenase family.
  
 
 0.930
KLLA0_C07777g
KLLA0C07777p; Belongs to the aldehyde dehydrogenase family.
  
 
 0.930
Your Current Organism:
Kluyveromyces lactis
NCBI taxonomy Id: 284590
Other names: K. lactis NRRL Y-1140, Kluyveromyces lactis NRRL Y-1140
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