STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SLDDelta 8-(E)-sphingolipid desaturase; Delta(8)-fatty-acid desaturase which introduces a double bond at the 8-position in the long-chain base (LCB) of ceramides. Required for the formation of the di-unsaturated sphingoid base (E,E)-sphinga- 4,8-dienine during glucosylceramide (GluCer) biosynthesis. (573 aa)    
Predicted Functional Partners:
KLLA0_B10307g
KLLA0B10307p.
  
 
 0.812
KLLA0_F08855g
KLLA0F08855p; Belongs to the sterol desaturase family.
  
 
 0.740
KLLA0_C10406g
KLLA0C10406p; Belongs to the sterol desaturase family.
  
 
 0.685
KLLA0_B08085g
KLLA0B08085p; Belongs to the sterol desaturase family.
  
 
 0.685
KLLA0_C10692g
Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.
  
 
 0.651
KLLA0_C05566g
Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.
  
 
 0.651
KLLA0_D08866g
KLLA0D08866p.
  
  
 0.638
KLLA0_D01639g
Ceramide very long chain fatty acid hydroxylase; Ceramide hydroxylase involved in the hydroxylation of sphingolipid-associated very long chain fatty acids. Postulated to hydroxylate the very long chain fatty acid of dihydroceramides and phytoceramides at C-2; Belongs to the sterol desaturase family. SCS7 subfamily.
      
 0.637
KLLA0_F18656g
KLLA0F18656p.
      
 0.578
KLLA0_C08239g
KLLA0C08239p; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
   
  
 0.551
Your Current Organism:
Kluyveromyces lactis
NCBI taxonomy Id: 284590
Other names: K. lactis NRRL Y-1140, Kluyveromyces lactis NRRL Y-1140
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