STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CWC26Pre-mRNA-splicing factor CWC26; Involved in pre-mRNA splicing. (268 aa)    
Predicted Functional Partners:
KLLA0_D13420g
KLLA0D13420p.
   
 0.998
KLLA0_D09526g
KLLA0D09526p.
   
 0.995
CEF1
Pre-mRNA-splicing factor CEF1; Involved in pre-mRNA splicing and cell cycle control.
    
 
 0.992
KLLA0_D03883g
KLLA0D03883p.
    
 
 0.989
KLLA0_C17798g
KLLA0C17798p.
    
 
 0.989
CWC2
Pre-mRNA-splicing factor CWC2; Involved in the first step of pre-mRNA splicing. Required for cell growth and cell cycle control. Plays a role in the levels of the U1, U4, U5 and U6 snRNAs and the maintenance of the U4/U6 snRNA complex. May provide the link between the 'nineteen complex' NTC spliceosome protein complex and the spliceosome through the U6 snRNA. Associates predominantly with U6 snRNAs in assembled active spliceosomes. Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic [...]
    
 
 0.988
KLLA0_F08283g
KLLA0F08283p.
    
   0.975
KLLA0_E21187g
KLLA0E21187p.
    
 
 0.969
KLLA0_F08481g
KLLA0F08481p.
    
 
 0.956
PRP45
Pre-mRNA-processing protein 45; Involved in pre-mRNA splicing.
    
 
 0.942
Your Current Organism:
Kluyveromyces lactis
NCBI taxonomy Id: 284590
Other names: K. lactis NRRL Y-1140, Kluyveromyces lactis NRRL Y-1140
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