STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
YALI0_E13123gYALI0E13123p. (547 aa)    
Predicted Functional Partners:
YALI0_A15950g
Histidine biosynthesis trifunctional protein.
  
 
 0.945
HIS1
ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of the enzymatic activity (By similarity).
  
 0.910
YALI0_B01034g
YALI0B01034p.
   
 0.886
YALI0_F26433g
YALI0F26433p.
  
  
 0.856
YALI0_E13277g
YALI0E13277p.
  
 
 0.853
YALI0_B04334g
YALI0B04334p.
  
 
 0.834
YALI0_B01760g
YALI0B01760p.
  
 
 0.830
ALA1
Alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. Belongs to the class-II aminoacyl-tRNA synthetase family.
  
 
 0.782
YALI0_D15268g
YALI0D15268p.
   
  
 0.763
YALI0_F20218g
YALI0F20218p; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 
 0.761
Your Current Organism:
Yarrowia lipolytica
NCBI taxonomy Id: 284591
Other names: Y. lipolytica CLIB122, Yarrowia lipolytica CLIB122
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.