STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Q6BHH4_DEBHAE3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (1814 aa)    
Predicted Functional Partners:
Q6BNP3_DEBHA
DEHA2E20042p.
   
 0.976
UBC2
Ubiquitin-conjugating enzyme E2 2; Catalyzes the covalent attachment of ubiquitin to other proteins. Plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation. Also involved in postreplication repair of UV-damaged DNA, in N-end rule-dependent protein degradation and in sporulation; Belongs to the ubiquitin-conjugating enzyme family.
    
 
 0.959
B5RTQ7_DEBHA
DEHA2D03454p.
    
 
 0.901
Q6BMT3_DEBHA
DEHA2F02816p.
   
 0.843
Q6BHS8_DEBHA
DEHA2G16082p.
   
 0.826
Q6BNV3_DEBHA
DEHA2E18788p.
    
  0.624
Q6BST3_DEBHA
DEHA2D06424p.
   
 
 0.582
Q6BNW5_DEBHA
DEHA2E18480p.
   
 0.488
Q6BYT6_DEBHA
DEHA2A07084p.
   
 
 0.482
Q6BJ34_DEBHA
DEHA2G05544p.
   
 
 0.470
Your Current Organism:
Debaryomyces hansenii
NCBI taxonomy Id: 284592
Other names: D. hansenii CBS767, Debaryomyces hansenii CBS767
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