Q6BXY4_DEBHA protein (Debaryomyces hansenii)

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Q6BXY4_DEBHA

Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (365 aa)

Predicted Functional Partners:

Q6BQE3_DEBHA

0.997

B5RV44_DEBHA

0.994

Q6BN83_DEBHA

0.994

YOS9

0.989

Q6BHY0_DEBHA

0.987

Q6BJA4_DEBHA

0.973

NPL4

0.968

Q6BV66_DEBHA

0.965

KAR2

0.964

Q6BYS0_DEBHA

0.959

Your Current Organism:

Debaryomyces hansenii

NCBI taxonomy Id: 284592
Other names: D. hansenii CBS767, Debaryomyces hansenii CBS767

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B5RV44_DEBHA	KAR2	B5RV44	Q6BZH1	DEHA2G06798p.	Endoplasmic reticulum chaperone BiP; Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER. Is required for secretory polypeptide translocation. May physically associate with SEC63 protein in the endoplasmic reticulum and this interaction may be regulated by ATP hydrolysis; Belongs to the heat shock protein 70 family.	0.677
B5RV44_DEBHA	NPL4	B5RV44	Q6BRJ9	DEHA2G06798p.	Nuclear protein localization protein 4; Involved in the import of nuclear-targeted proteins into the nucleus and the export of poly(A) RNA out of the nucleus. Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway (By similarity); Belongs to the NPL4 family.	0.611
B5RV44_DEBHA	Q6BHY0_DEBHA	B5RV44	Q6BHY0	DEHA2G06798p.	DEHA2G14960p; Belongs to the AAA ATPase family.	0.987
B5RV44_DEBHA	Q6BJA4_DEBHA	B5RV44	Q6BJA4	DEHA2G06798p.	DEHA2G03938p.	0.514
B5RV44_DEBHA	Q6BN83_DEBHA	B5RV44	Q6BN83	DEHA2G06798p.	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	0.999
B5RV44_DEBHA	Q6BQE3_DEBHA	B5RV44	Q6BQE3	DEHA2G06798p.	DEHA2E05852p.	0.997
B5RV44_DEBHA	Q6BXY4_DEBHA	B5RV44	Q6BXY4	DEHA2G06798p.	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	0.994
B5RV44_DEBHA	YOS9	B5RV44	Q6BJ08	DEHA2G06798p.	Protein OS-9 homolog; Lectin involved in the quality control of the secretory pathway. As a member of the endoplasmic reticulum-associated degradation lumenal (ERAD-L) surveillance system, targets misfolded endoplasmic reticulum lumenal glycoproteins for degradation (By similarity).	0.998
KAR2	B5RV44_DEBHA	Q6BZH1	B5RV44	Endoplasmic reticulum chaperone BiP; Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER. Is required for secretory polypeptide translocation. May physically associate with SEC63 protein in the endoplasmic reticulum and this interaction may be regulated by ATP hydrolysis; Belongs to the heat shock protein 70 family.	DEHA2G06798p.	0.677
KAR2	Q6BHY0_DEBHA	Q6BZH1	Q6BHY0	Endoplasmic reticulum chaperone BiP; Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER. Is required for secretory polypeptide translocation. May physically associate with SEC63 protein in the endoplasmic reticulum and this interaction may be regulated by ATP hydrolysis; Belongs to the heat shock protein 70 family.	DEHA2G14960p; Belongs to the AAA ATPase family.	0.625
KAR2	Q6BN83_DEBHA	Q6BZH1	Q6BN83	Endoplasmic reticulum chaperone BiP; Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER. Is required for secretory polypeptide translocation. May physically associate with SEC63 protein in the endoplasmic reticulum and this interaction may be regulated by ATP hydrolysis; Belongs to the heat shock protein 70 family.	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	0.857
KAR2	Q6BQE3_DEBHA	Q6BZH1	Q6BQE3	Endoplasmic reticulum chaperone BiP; Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER. Is required for secretory polypeptide translocation. May physically associate with SEC63 protein in the endoplasmic reticulum and this interaction may be regulated by ATP hydrolysis; Belongs to the heat shock protein 70 family.	DEHA2E05852p.	0.693
KAR2	Q6BXY4_DEBHA	Q6BZH1	Q6BXY4	Endoplasmic reticulum chaperone BiP; Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER. Is required for secretory polypeptide translocation. May physically associate with SEC63 protein in the endoplasmic reticulum and this interaction may be regulated by ATP hydrolysis; Belongs to the heat shock protein 70 family.	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	0.964
KAR2	YOS9	Q6BZH1	Q6BJ08	Endoplasmic reticulum chaperone BiP; Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER. Is required for secretory polypeptide translocation. May physically associate with SEC63 protein in the endoplasmic reticulum and this interaction may be regulated by ATP hydrolysis; Belongs to the heat shock protein 70 family.	Protein OS-9 homolog; Lectin involved in the quality control of the secretory pathway. As a member of the endoplasmic reticulum-associated degradation lumenal (ERAD-L) surveillance system, targets misfolded endoplasmic reticulum lumenal glycoproteins for degradation (By similarity).	0.763
NPL4	B5RV44_DEBHA	Q6BRJ9	B5RV44	Nuclear protein localization protein 4; Involved in the import of nuclear-targeted proteins into the nucleus and the export of poly(A) RNA out of the nucleus. Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway (By similarity); Belongs to the NPL4 family.	DEHA2G06798p.	0.611
NPL4	Q6BHY0_DEBHA	Q6BRJ9	Q6BHY0	Nuclear protein localization protein 4; Involved in the import of nuclear-targeted proteins into the nucleus and the export of poly(A) RNA out of the nucleus. Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway (By similarity); Belongs to the NPL4 family.	DEHA2G14960p; Belongs to the AAA ATPase family.	0.999
NPL4	Q6BJA4_DEBHA	Q6BRJ9	Q6BJA4	Nuclear protein localization protein 4; Involved in the import of nuclear-targeted proteins into the nucleus and the export of poly(A) RNA out of the nucleus. Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway (By similarity); Belongs to the NPL4 family.	DEHA2G03938p.	0.999
NPL4	Q6BN83_DEBHA	Q6BRJ9	Q6BN83	Nuclear protein localization protein 4; Involved in the import of nuclear-targeted proteins into the nucleus and the export of poly(A) RNA out of the nucleus. Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway (By similarity); Belongs to the NPL4 family.	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	0.973
NPL4	Q6BQE3_DEBHA	Q6BRJ9	Q6BQE3	Nuclear protein localization protein 4; Involved in the import of nuclear-targeted proteins into the nucleus and the export of poly(A) RNA out of the nucleus. Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway (By similarity); Belongs to the NPL4 family.	DEHA2E05852p.	0.730
NPL4	Q6BXY4_DEBHA	Q6BRJ9	Q6BXY4	Nuclear protein localization protein 4; Involved in the import of nuclear-targeted proteins into the nucleus and the export of poly(A) RNA out of the nucleus. Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway (By similarity); Belongs to the NPL4 family.	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	0.968