Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.
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Neighborhood
Groups of genes that are frequently observed in each other's genomic neighborhood.
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Textmining
Automated, unsupervised textmining - searching for proteins that are frequently mentioned together.
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Fusion
Genes that are sometimes fused into single open reading frames.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
Node Content
empty nodes: proteins of unknown 3D structure
filled nodes: a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Q6FL57_CANGA
Uncharacterized protein. (505 aa)
Predicted Functional Partners:
POG1
Transcriptional activator POG1; Transcriptional activator which promotes cell cycle recovery, after pheromone induced G1 arrest. May also be involved in stress- resistance (By similarity); Belongs to the POG1 family.
0.411
Your Current Organism:
Candida glabrata
NCBI taxonomy Id: 284593 Other names: Candida glabrata ATCC 2001, Candida glabrata ATCC2001, Candida glabrata CBS 138, Candida glabrata CBS138, [. glabrata CBS 138, [Candida] glabrata CBS 138
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
node1
node2
node1 accession
node2 accession
node1 annotation
node2 annotation
score
POG1
Q6FL57_CANGA
Q6FSQ6
Q6FL57
Transcriptional activator POG1; Transcriptional activator which promotes cell cycle recovery, after pheromone induced G1 arrest. May also be involved in stress- resistance (By similarity); Belongs to the POG1 family.
Uncharacterized protein.
0.411
Q6FL57_CANGA
POG1
Q6FL57
Q6FSQ6
Uncharacterized protein.
Transcriptional activator POG1; Transcriptional activator which promotes cell cycle recovery, after pheromone induced G1 arrest. May also be involved in stress- resistance (By similarity); Belongs to the POG1 family.
0.411
Network Stats
Network Stats analysis is still ongoing, please wait ...
Functional enrichments in your networkNote: some enrichments may be expected here (why?) disable highlightexplain columns
Enrichment analysis is still ongoing, please wait ...
Statistical background
For the above enrichment analysis, the following statistical background is assumed: