node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CDC48 | PNG1 | Q6FNS8 | Q6FRU8 | Uncharacterized protein; Belongs to the AAA ATPase family. | Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase; Specifically deglycosylates the denatured form of N-linked glycoproteins in the cytoplasm and assists their proteasome-mediated degradation. Cleaves the beta-aspartyl-glucosamine (GlcNAc) of the glycan and the amide side chain of Asn, converting Asn to Asp. Prefers proteins containing high-mannose over those bearing complex type oligosaccharides. Can recognize misfolded proteins in the endoplasmic reticulum that are exported to the cytosol to be destroyed and deglycosylate them, while it has no activity toward native proteins [...] | 0.789 |
CDC48 | Q6FJL4_CANGA | Q6FNS8 | Q6FJL4 | Uncharacterized protein; Belongs to the AAA ATPase family. | Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. | 0.992 |
CDC48 | Q6FK42_CANGA | Q6FNS8 | Q6FK42 | Uncharacterized protein; Belongs to the AAA ATPase family. | UBX domain-containing protein. | 0.988 |
CDC48 | Q6FLR4_CANGA | Q6FNS8 | Q6FLR4 | Uncharacterized protein; Belongs to the AAA ATPase family. | Uncharacterized protein. | 0.834 |
CDC48 | Q6FPC6_CANGA | Q6FNS8 | Q6FPC6 | Uncharacterized protein; Belongs to the AAA ATPase family. | UBX domain-containing protein. | 0.776 |
CDC48 | Q6FQN2_CANGA | Q6FNS8 | Q6FQN2 | Uncharacterized protein; Belongs to the AAA ATPase family. | AAA domain-containing protein; Belongs to the AAA ATPase family. | 0.735 |
CDC48 | Q6FUK1_CANGA | Q6FNS8 | Q6FUK1 | Uncharacterized protein; Belongs to the AAA ATPase family. | Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. | 0.991 |
CDC48 | Q6FVF5_CANGA | Q6FNS8 | Q6FVF5 | Uncharacterized protein; Belongs to the AAA ATPase family. | RING-type domain-containing protein. | 0.994 |
CDC48 | Q6FVG0_CANGA | Q6FNS8 | Q6FVG0 | Uncharacterized protein; Belongs to the AAA ATPase family. | Ubiquitin-like domain-containing protein. | 0.599 |
PNG1 | CDC48 | Q6FRU8 | Q6FNS8 | Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase; Specifically deglycosylates the denatured form of N-linked glycoproteins in the cytoplasm and assists their proteasome-mediated degradation. Cleaves the beta-aspartyl-glucosamine (GlcNAc) of the glycan and the amide side chain of Asn, converting Asn to Asp. Prefers proteins containing high-mannose over those bearing complex type oligosaccharides. Can recognize misfolded proteins in the endoplasmic reticulum that are exported to the cytosol to be destroyed and deglycosylate them, while it has no activity toward native proteins [...] | Uncharacterized protein; Belongs to the AAA ATPase family. | 0.789 |
PNG1 | Q6FJL4_CANGA | Q6FRU8 | Q6FJL4 | Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase; Specifically deglycosylates the denatured form of N-linked glycoproteins in the cytoplasm and assists their proteasome-mediated degradation. Cleaves the beta-aspartyl-glucosamine (GlcNAc) of the glycan and the amide side chain of Asn, converting Asn to Asp. Prefers proteins containing high-mannose over those bearing complex type oligosaccharides. Can recognize misfolded proteins in the endoplasmic reticulum that are exported to the cytosol to be destroyed and deglycosylate them, while it has no activity toward native proteins [...] | Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. | 0.635 |
PNG1 | Q6FLR4_CANGA | Q6FRU8 | Q6FLR4 | Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase; Specifically deglycosylates the denatured form of N-linked glycoproteins in the cytoplasm and assists their proteasome-mediated degradation. Cleaves the beta-aspartyl-glucosamine (GlcNAc) of the glycan and the amide side chain of Asn, converting Asn to Asp. Prefers proteins containing high-mannose over those bearing complex type oligosaccharides. Can recognize misfolded proteins in the endoplasmic reticulum that are exported to the cytosol to be destroyed and deglycosylate them, while it has no activity toward native proteins [...] | Uncharacterized protein. | 0.998 |
PNG1 | Q6FPC6_CANGA | Q6FRU8 | Q6FPC6 | Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase; Specifically deglycosylates the denatured form of N-linked glycoproteins in the cytoplasm and assists their proteasome-mediated degradation. Cleaves the beta-aspartyl-glucosamine (GlcNAc) of the glycan and the amide side chain of Asn, converting Asn to Asp. Prefers proteins containing high-mannose over those bearing complex type oligosaccharides. Can recognize misfolded proteins in the endoplasmic reticulum that are exported to the cytosol to be destroyed and deglycosylate them, while it has no activity toward native proteins [...] | UBX domain-containing protein. | 0.620 |
PNG1 | Q6FQN2_CANGA | Q6FRU8 | Q6FQN2 | Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase; Specifically deglycosylates the denatured form of N-linked glycoproteins in the cytoplasm and assists their proteasome-mediated degradation. Cleaves the beta-aspartyl-glucosamine (GlcNAc) of the glycan and the amide side chain of Asn, converting Asn to Asp. Prefers proteins containing high-mannose over those bearing complex type oligosaccharides. Can recognize misfolded proteins in the endoplasmic reticulum that are exported to the cytosol to be destroyed and deglycosylate them, while it has no activity toward native proteins [...] | AAA domain-containing protein; Belongs to the AAA ATPase family. | 0.979 |
PNG1 | Q6FUK1_CANGA | Q6FRU8 | Q6FUK1 | Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase; Specifically deglycosylates the denatured form of N-linked glycoproteins in the cytoplasm and assists their proteasome-mediated degradation. Cleaves the beta-aspartyl-glucosamine (GlcNAc) of the glycan and the amide side chain of Asn, converting Asn to Asp. Prefers proteins containing high-mannose over those bearing complex type oligosaccharides. Can recognize misfolded proteins in the endoplasmic reticulum that are exported to the cytosol to be destroyed and deglycosylate them, while it has no activity toward native proteins [...] | Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. | 0.783 |
PNG1 | Q6FVF5_CANGA | Q6FRU8 | Q6FVF5 | Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase; Specifically deglycosylates the denatured form of N-linked glycoproteins in the cytoplasm and assists their proteasome-mediated degradation. Cleaves the beta-aspartyl-glucosamine (GlcNAc) of the glycan and the amide side chain of Asn, converting Asn to Asp. Prefers proteins containing high-mannose over those bearing complex type oligosaccharides. Can recognize misfolded proteins in the endoplasmic reticulum that are exported to the cytosol to be destroyed and deglycosylate them, while it has no activity toward native proteins [...] | RING-type domain-containing protein. | 0.802 |
PNG1 | Q6FVG0_CANGA | Q6FRU8 | Q6FVG0 | Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase; Specifically deglycosylates the denatured form of N-linked glycoproteins in the cytoplasm and assists their proteasome-mediated degradation. Cleaves the beta-aspartyl-glucosamine (GlcNAc) of the glycan and the amide side chain of Asn, converting Asn to Asp. Prefers proteins containing high-mannose over those bearing complex type oligosaccharides. Can recognize misfolded proteins in the endoplasmic reticulum that are exported to the cytosol to be destroyed and deglycosylate them, while it has no activity toward native proteins [...] | Ubiquitin-like domain-containing protein. | 0.927 |
PNG1 | Q6FWV5_CANGA | Q6FRU8 | Q6FWV5 | Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase; Specifically deglycosylates the denatured form of N-linked glycoproteins in the cytoplasm and assists their proteasome-mediated degradation. Cleaves the beta-aspartyl-glucosamine (GlcNAc) of the glycan and the amide side chain of Asn, converting Asn to Asp. Prefers proteins containing high-mannose over those bearing complex type oligosaccharides. Can recognize misfolded proteins in the endoplasmic reticulum that are exported to the cytosol to be destroyed and deglycosylate them, while it has no activity toward native proteins [...] | Uncharacterized protein. | 0.786 |
Q6FJL4_CANGA | CDC48 | Q6FJL4 | Q6FNS8 | Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. | Uncharacterized protein; Belongs to the AAA ATPase family. | 0.992 |
Q6FJL4_CANGA | PNG1 | Q6FJL4 | Q6FRU8 | Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. | Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase; Specifically deglycosylates the denatured form of N-linked glycoproteins in the cytoplasm and assists their proteasome-mediated degradation. Cleaves the beta-aspartyl-glucosamine (GlcNAc) of the glycan and the amide side chain of Asn, converting Asn to Asp. Prefers proteins containing high-mannose over those bearing complex type oligosaccharides. Can recognize misfolded proteins in the endoplasmic reticulum that are exported to the cytosol to be destroyed and deglycosylate them, while it has no activity toward native proteins [...] | 0.635 |