STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LYS5L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase; Catalyzes the transfer of a 4'-phosphopantetheine moiety from coenzyme A to a serine residue of acceptor proteins, such as alpha- aminoadipate reductase. Necessary for alpha-aminoadipate reductase activity (By similarity); Belongs to the P-Pant transferase superfamily. AcpS family. (258 aa)    
Predicted Functional Partners:
Q6FU82_CANGA
Uncharacterized protein.
   
 
 0.914
LYS2
L-2-aminoadipate reductase large subunit; Catalyzes the activation of alpha-aminoadipate by ATP- dependent adenylation and the reduction of activated alpha-aminoadipate by NADPH. The activated alpha-aminoadipate is bound to the phosphopantheinyl group of the enzyme itself before it is reduced to (S)-2-amino-6-oxohexanoate.
  
 0.910
Q6FPF9_CANGA
Uncharacterized protein.
  
  
 0.803
URA5
Pribosyltran domain-containing protein.
    
 
 0.723
Q6FPL1_CANGA
PKS_KS domain-containing protein; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
  
  
 0.687
LYS4
Homoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis.
   
  
 0.678
THR4
Uncharacterized protein.
     
 0.602
URA3
Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family.
    
 
 0.594
LYS1
Saccharopine dehydrogenase [NAD(+), L-lysine-forming]; Catalyzes the NAD(+)-dependent cleavage of saccharopine to L- lysine and 2-oxoglutarate, the final step in the alpha-aminoadipate (AAA) pathway for lysin biosynthesis.
  
  
 0.531
Q6FPD5_CANGA
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
  
 
 0.530
Your Current Organism:
Candida glabrata
NCBI taxonomy Id: 284593
Other names: Candida glabrata ATCC 2001, Candida glabrata ATCC2001, Candida glabrata CBS 138, Candida glabrata CBS138, [. glabrata CBS 138, [Candida] glabrata CBS 138
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.