STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BIG1Protein BIG1; Required for normal beta-1,6-glucan synthesis; Belongs to the BIG1 family. (319 aa)    
Predicted Functional Partners:
ROT1
Protein ROT1; Required for normal levels of the cell wall 1,6-beta-glucan. Involved in a protein folding machinery chaperoning proteins acting in various physiological processes including cell wall synthesis and lysis of autophagic bodies (By similarity); Belongs to the ROT1 family.
    
 
 0.901
KRE9
Cell wall synthesis protein KRE9; Involved in cell wall beta(1->6) glucan synthesis.
    
 
 0.764
Q6FV20_CANGA
Uncharacterized protein.
    
 
 0.536
Q6FIS5_CANGA
OBG-type G domain-containing protein.
   
    0.513
HUT1
UDP-galactose transporter homolog 1; May be involved in specific transport of UDP-Gal from the cytosol to the Golgi lumen. Involved in the maintenance of optimal conditions for the folding of secretory pathway proteins in the endoplasmic reticulum (By similarity); Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
   
   0.477
KNH1
Cell wall synthesis protein KNH1; Involved in cell wall beta(1->6) glucan synthesis.
    
 
 0.463
ROT2
Gal_mutarotas_2 domain-containing protein; Belongs to the glycosyl hydrolase 31 family.
   
 
 0.445
Q6FXP6_CANGA
RPOLD domain-containing protein.
   
    0.410
Your Current Organism:
Candida glabrata
NCBI taxonomy Id: 284593
Other names: Candida glabrata ATCC 2001, Candida glabrata ATCC2001, Candida glabrata CBS 138, Candida glabrata CBS138, [. glabrata CBS 138, [Candida] glabrata CBS 138
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.