node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EPA2 | ISU1 | Q6FUW4 | Q6FJY3 | PA14 domain-containing protein. | Iron sulfur cluster assembly protein 1, mitochondrial; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. First, a [2Fe-2S] cluster is transiently assembled on the scaffold protein ISU1. In a second step, the cluster is released from ISU1, transferred to a glutaredoxin, followed by the formation of mitochondrial [2Fe-2S] proteins, the synthesis of [4Fe-4S] clusters and their target-specific insertion into the recipient apoproteins. Cluster a [...] | 0.674 |
EPA2 | Q6FS34_CANGA | Q6FUW4 | Q6FS34 | PA14 domain-containing protein. | Aminotran_5 domain-containing protein. | 0.909 |
EPA2 | Q6FSG7_CANGA | Q6FUW4 | Q6FSG7 | PA14 domain-containing protein. | 2Fe-2S ferredoxin-type domain-containing protein. | 0.687 |
EPA2 | YFH1 | Q6FUW4 | Q6FJK3 | PA14 domain-containing protein. | Uncharacterized protein. | 0.844 |
ISA1 | ISU1 | Q6FV99 | Q6FJY3 | Fe-S_biosyn domain-containing protein. | Iron sulfur cluster assembly protein 1, mitochondrial; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. First, a [2Fe-2S] cluster is transiently assembled on the scaffold protein ISU1. In a second step, the cluster is released from ISU1, transferred to a glutaredoxin, followed by the formation of mitochondrial [2Fe-2S] proteins, the synthesis of [4Fe-4S] clusters and their target-specific insertion into the recipient apoproteins. Cluster a [...] | 0.731 |
ISA1 | NFU1 | Q6FV99 | Q6FLP4 | Fe-S_biosyn domain-containing protein. | Nfu_N domain-containing protein. | 0.730 |
ISA1 | Q6FS34_CANGA | Q6FV99 | Q6FS34 | Fe-S_biosyn domain-containing protein. | Aminotran_5 domain-containing protein. | 0.738 |
ISA1 | Q6FSG7_CANGA | Q6FV99 | Q6FSG7 | Fe-S_biosyn domain-containing protein. | 2Fe-2S ferredoxin-type domain-containing protein. | 0.576 |
ISA1 | Q6FWB4_CANGA | Q6FV99 | Q6FWB4 | Fe-S_biosyn domain-containing protein. | Fe-S_biosyn domain-containing protein. | 0.844 |
ISA1 | Q6FXV4_CANGA | Q6FV99 | Q6FXV4 | Fe-S_biosyn domain-containing protein. | J domain-containing protein. | 0.718 |
ISU1 | EPA2 | Q6FJY3 | Q6FUW4 | Iron sulfur cluster assembly protein 1, mitochondrial; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. First, a [2Fe-2S] cluster is transiently assembled on the scaffold protein ISU1. In a second step, the cluster is released from ISU1, transferred to a glutaredoxin, followed by the formation of mitochondrial [2Fe-2S] proteins, the synthesis of [4Fe-4S] clusters and their target-specific insertion into the recipient apoproteins. Cluster a [...] | PA14 domain-containing protein. | 0.674 |
ISU1 | ISA1 | Q6FJY3 | Q6FV99 | Iron sulfur cluster assembly protein 1, mitochondrial; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. First, a [2Fe-2S] cluster is transiently assembled on the scaffold protein ISU1. In a second step, the cluster is released from ISU1, transferred to a glutaredoxin, followed by the formation of mitochondrial [2Fe-2S] proteins, the synthesis of [4Fe-4S] clusters and their target-specific insertion into the recipient apoproteins. Cluster a [...] | Fe-S_biosyn domain-containing protein. | 0.731 |
ISU1 | NFU1 | Q6FJY3 | Q6FLP4 | Iron sulfur cluster assembly protein 1, mitochondrial; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. First, a [2Fe-2S] cluster is transiently assembled on the scaffold protein ISU1. In a second step, the cluster is released from ISU1, transferred to a glutaredoxin, followed by the formation of mitochondrial [2Fe-2S] proteins, the synthesis of [4Fe-4S] clusters and their target-specific insertion into the recipient apoproteins. Cluster a [...] | Nfu_N domain-containing protein. | 0.698 |
ISU1 | Q6FPL9_CANGA | Q6FJY3 | Q6FPL9 | Iron sulfur cluster assembly protein 1, mitochondrial; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. First, a [2Fe-2S] cluster is transiently assembled on the scaffold protein ISU1. In a second step, the cluster is released from ISU1, transferred to a glutaredoxin, followed by the formation of mitochondrial [2Fe-2S] proteins, the synthesis of [4Fe-4S] clusters and their target-specific insertion into the recipient apoproteins. Cluster a [...] | Uncharacterized protein; Belongs to the complex I LYR family. | 0.915 |
ISU1 | Q6FS34_CANGA | Q6FJY3 | Q6FS34 | Iron sulfur cluster assembly protein 1, mitochondrial; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. First, a [2Fe-2S] cluster is transiently assembled on the scaffold protein ISU1. In a second step, the cluster is released from ISU1, transferred to a glutaredoxin, followed by the formation of mitochondrial [2Fe-2S] proteins, the synthesis of [4Fe-4S] clusters and their target-specific insertion into the recipient apoproteins. Cluster a [...] | Aminotran_5 domain-containing protein. | 0.986 |
ISU1 | Q6FSG7_CANGA | Q6FJY3 | Q6FSG7 | Iron sulfur cluster assembly protein 1, mitochondrial; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. First, a [2Fe-2S] cluster is transiently assembled on the scaffold protein ISU1. In a second step, the cluster is released from ISU1, transferred to a glutaredoxin, followed by the formation of mitochondrial [2Fe-2S] proteins, the synthesis of [4Fe-4S] clusters and their target-specific insertion into the recipient apoproteins. Cluster a [...] | 2Fe-2S ferredoxin-type domain-containing protein. | 0.871 |
ISU1 | Q6FWB4_CANGA | Q6FJY3 | Q6FWB4 | Iron sulfur cluster assembly protein 1, mitochondrial; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. First, a [2Fe-2S] cluster is transiently assembled on the scaffold protein ISU1. In a second step, the cluster is released from ISU1, transferred to a glutaredoxin, followed by the formation of mitochondrial [2Fe-2S] proteins, the synthesis of [4Fe-4S] clusters and their target-specific insertion into the recipient apoproteins. Cluster a [...] | Fe-S_biosyn domain-containing protein. | 0.717 |
ISU1 | Q6FXV4_CANGA | Q6FJY3 | Q6FXV4 | Iron sulfur cluster assembly protein 1, mitochondrial; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. First, a [2Fe-2S] cluster is transiently assembled on the scaffold protein ISU1. In a second step, the cluster is released from ISU1, transferred to a glutaredoxin, followed by the formation of mitochondrial [2Fe-2S] proteins, the synthesis of [4Fe-4S] clusters and their target-specific insertion into the recipient apoproteins. Cluster a [...] | J domain-containing protein. | 0.956 |
ISU1 | YFH1 | Q6FJY3 | Q6FJK3 | Iron sulfur cluster assembly protein 1, mitochondrial; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. First, a [2Fe-2S] cluster is transiently assembled on the scaffold protein ISU1. In a second step, the cluster is released from ISU1, transferred to a glutaredoxin, followed by the formation of mitochondrial [2Fe-2S] proteins, the synthesis of [4Fe-4S] clusters and their target-specific insertion into the recipient apoproteins. Cluster a [...] | Uncharacterized protein. | 0.932 |
ISU1 | mge1 | Q6FJY3 | Q6FPH2 | Iron sulfur cluster assembly protein 1, mitochondrial; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. First, a [2Fe-2S] cluster is transiently assembled on the scaffold protein ISU1. In a second step, the cluster is released from ISU1, transferred to a glutaredoxin, followed by the formation of mitochondrial [2Fe-2S] proteins, the synthesis of [4Fe-4S] clusters and their target-specific insertion into the recipient apoproteins. Cluster a [...] | GrpE protein homolog, mitochondrial; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of SSC1 to substrate proteins (By similarity). | 0.699 |