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VAC8 protein (Candida glabrata) - STRING interaction network
"VAC8" - Hypothetical protein in Candida glabrata
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VAC8Hypothetical protein; Functions in both vacuole inheritance and protein targeting from the cytoplasm to vacuole (582 aa)    
Predicted Functional Partners:
ATG13
Hypothetical protein; Activates the ATG1 kinase in a nutritional condition dependent manner through the TOR pathway, leading to autophagy. Also involved in cytoplasm to vacuole transport (Cvt) and more specifically in Cvt vesicle formation. Seems to play a role in the switching machinery regulating the conversion between the Cvt pathway and autophagy. Finally, ATG13 is also required for glycogen storage during stationary phase (By similarity) (660 aa)
       
  0.927
PFA3
Hypothetical protein; Palmitoyltransferase specific for VAC8. Palmitoylates VAC8 at one or more of its N-terminal cysteine residues, which is required for its proper membrane localization (By similarity) (332 aa)
     
 
  0.658
XP_444983.1
Hypothetical protein (430 aa)
       
 
  0.643
ATG1
Hypothetical protein; Serine/threonine protein kinase involved in the cytoplasm to vacuole transport (Cvt) and found to be essential in autophagy, where it is required for the formation of autophagosomes. Involved in the clearance of protein aggregates which cannot be efficiently cleared by the proteasome. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS prod [...] (942 aa)
     
 
  0.619
XP_446569.1
Hypothetical protein (245 aa)
       
 
  0.591
XP_449144.1
Hypothetical protein (173 aa)
       
 
  0.588
XP_447696.1
Hypothetical protein (172 aa)
       
 
  0.588
IML1
Hypothetical protein (1804 aa)
       
      0.548
XP_445238.1
Hypothetical protein (705 aa)
       
 
  0.529
XP_449228.1
Hypothetical protein (225 aa)
       
 
  0.513
Your Current Organism:
Candida glabrata
NCBI taxonomy Id: 284593
Other names: C. glabrata, C. glabrata CBS 138, Candida glabrata, Candida glabrata ATCC 2001, Candida glabrata ATCC2001, Candida glabrata CBS 138, Candida glabrata CBS138, Nakaseomyces, Torulopsis glabrata, m. Nakaseomyces, mitosporic Nakaseomyces
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