STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AGOS_AGR344WAGR344Wp; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (390 aa)    
Predicted Functional Partners:
AGOS_ACL118C
ACL118Cp.
     
 0.982
AGOS_AFR431C
Phosphatidyl-N-methylethanolamine N-methyltransferase; Catalyzes the second two steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylmonomethylethanolamine (PMME) to phosphatidyldimethylethanolamine (PDME) and of PDME to phosphatidylcholine (PC).
    
 0.960
AGOS_AFR071W
Phospholipase.
     
 0.948
AGOS_AFL195W
AFL195Wp.
     
 0.940
AGOS_AGR271C
AGR271Cp; Belongs to the membrane-bound acyltransferase family.
     
 0.938
AGOS_AFR693C
AFR693Cp.
    
 0.926
AGOS_AAL084W
AAL084Wp.
    
 0.926
DGK1
CTP-dependent diacylglycerol kinase 1; CTP-dependent diacylglycerol kinase that catalyzes the phosphorylation of diacylglycerol (DAG) to phosphatidate (PA). Controls phosphatidate levels at the nuclear envelope. May be involved in vesicle trafficking between the endoplasmic reticulum and the Golgi apparatus. Involved in pre-tRNA splicing (By similarity). Belongs to the DGK1 family.
     
 0.905
AGOS_ADR231C
Patatin-like phospholipase domain-containing protein; Lipid hydrolase; Belongs to the PLPL family.
     
 0.902
PAC1
Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. Plays a central role in positioning the mitotic spindle at the bud neck during cell division. Targets cytoplasmic dynein to microtubule plus ends, thereby promoting dynein- mediated microtubule sliding along the bud cortex and consequently the movement of the mitotic spindle to the bud neck.
     
  0.900
Your Current Organism:
Eremothecium gossypii
NCBI taxonomy Id: 284811
Other names: Ashbya gossypii ATCC 10895, E. gossypii ATCC 10895, Eremothecium gossypii ATCC 10895
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.