STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AGOS_ABL057WABL057Wp. (234 aa)    
Predicted Functional Partners:
AGOS_AFL085C
AFL085Cp.
    
 0.974
AGOS_ADL388W
ADL388Wp.
   
 0.971
CPR6
Peptidyl-prolyl cis-trans isomerase D; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
   
 0.957
HSP82
Heat shock protein HSP82; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function (By similarity); Belongs to the heat shock protein 90 family.
   
 0.952
AGOS_AAR087C
AAR087Cp.
   
 0.947
AGOS_AAR083C
Serine/threonine-protein phosphatase.
    
 0.938
AGOS_AEL224W
AEL224Wp.
   
 0.937
AGOS_AEL062C
AEL062Cp.
   
 0.898
AGOS_AGL090W
AGL090Wp.
   
 
 0.842
DIA2
Protein DIA2; F-box protein component of a SCF ubiquitin ligase complex involved in ubiquitin-dependent protein degradation. The SCF-DIA2 complex is specifically involved in the pheromone induced degradation of phosphorylated TEC1. Involved in DNA replication, genome stability, and the control of cell cycle, probably through its association to replication origins to facilitate the ubiquitination of another origin- binding protein (By similarity).
   
 0.794
Your Current Organism:
Eremothecium gossypii
NCBI taxonomy Id: 284811
Other names: Ashbya gossypii ATCC 10895, E. gossypii ATCC 10895, Eremothecium gossypii ATCC 10895
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.