STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pun1SUR7 family protein pun1; Contributes to the wild-type cellular response to nitrogen stress through signaling pathways that regulate the expression of genes involved in amino acid biosynthesis. Required for wild-type filamentous growth, cell growth, and cell-cell adhesion (By similarity). Belongs to the SUR7 family. (288 aa)    
Predicted Functional Partners:
mug33
Meiotically up-regulated gene 33 protein; Has a role in meiosis.
      
 0.871
crr1
Probable glycosidase C21B10.07.
   
  
 0.786
rcr1
Uncharacterized protein C19C7.05.
   
  
 0.762
fhn1
Non-classical export protein 2 homolog; Involved in membrane organization and might act as a sensor of sphingolipids that regulates plasma membrane function. Involved in a novel pathway of export of proteins that lack a cleavable signal sequence; Belongs to the NCE102 family.
      
 0.759
pil1
Probable sphingolipid long chain base-responsive protein pil1; Negative regulator of cell wall integrity (CWI) in unstressed cells, probably by inhibiting protein kinase ksg1/ppk21 activity and regulating their downstream CWI pathways pck2-MAP kinase pathway and protein kinase gad8 pathway. Activity may be regulated by the transient increase of sphingolipid long chain bases (LCBs) during heat stress (By similarity).
      
 0.750
dfg502
Putative mannan endo-1,6-alpha-mannosidase C1198.07c; Belongs to the glycosyl hydrolase 76 family.
   
  
 0.749
slm1
Cytoskeletal signaling protein slm1; Effector of the TORC2- and calcineurin-signaling pathways. Mediates actin polarization via inhibition of calcineurin-dependent transcription (By similarity).
      
 0.606
pil2
Probable sphingolipid long chain base-responsive protein pil2; Negative regulator of cell wall integrity (CWI) in unstressed cells, probably by inhibiting protein kinase ksg1/ppk21 activity and regulating their downstream CWI pathways pck2-MAP kinase pathway and protein kinase gad8 pathway. Activity may be regulated by the transient increase of sphingolipid long chain bases (LCBs) during heat stress (By similarity).
      
 0.573
pvg1
Pyruvyl transferase 1; Involved in cell wall biogenesis. Has a role in the addition of Gal-beta1,3 moieties to galactomannans and their subsequent pyruvylation.
      
 0.548
omh1
O-glycoside alpha-1,2-mannosyltransferase omh1; Mannosyltransferase involved in O-glycosylation of cell wall and secreted proteins. Plays a major role in extending alpha-1,2-linked mannose in the O-glycan pathway; Belongs to the glycosyltransferase 15 family.
   
  
 0.523
Your Current Organism:
Schizosaccharomyces pombe
NCBI taxonomy Id: 284812
Other names: S. pombe 972h-, Schizosaccharomyces pombe 972h-
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