STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ntp1Neutral trehalase; Belongs to the glycosyl hydrolase 37 family. (735 aa)    
Predicted Functional Partners:
tps1
Alpha,alpha-trehalose-phosphate synthase [UDP-forming]; Appears to have a role in spore germination. In S.pombe it appears to have no role in the control of the initial steps of glycolysis.
  
 0.996
tpp1
Trehalose-phosphatase; In the C-terminal section; belongs to the trehalose phosphatase family.
  
 0.989
tps2
Trehalose-phosphatase; Phosphatase catalytic subunit of the trehalose synthase complex that catalyzes the production of trehalose from glucose-6- phosphate and UDP-glucose in a two step process; In the N-terminal section; belongs to the glycosyltransferase 20 family.
  
 0.987
tps3
Putative alpha,alpha-trehalose-phosphate synthase [UDP-forming] 106 kDa subunit.
  
 0.982
SPAC22F8.05
Putative alpha,alpha-trehalose-phosphate synthase [UDP-forming] 100 kDa subunit.
  
 0.967
ctt1
Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
   
  
 0.926
pka1
cAMP-dependent protein kinase catalytic subunit.
   
 
 0.793
pgm1
Phosphoglucomutase; Catalyzes the reversible interconversion of glucose 1- phosphate and glucose 6-phosphate. Key enzyme in hexose metabolism. The reverse reaction is an essential step for biosynthesis because glucose 1-phosphate is the starting point for the synthesis of UDP-glucose, which acts as a precursor for the synthesis of oligosaccharides and trehalose; Belongs to the phosphohexose mutase family.
  
  
 0.786
gpx1
Glutathione peroxidase-like peroxiredoxin gpx1; Glutathione peroxidase-like protein that protects cells during oxidative stress. Has peroxidase activity reducing hydrogen peroxide, alkyl and phospholipid hydroperoxides using preferentially thioredoxin as a reducing power. May act as a scavenger of H(2)O(2). Belongs to the glutathione peroxidase family.
 
 
  
 0.771
atf1
Transcription factor atf1; Transcription factor required for sexual development and entry into stationary phase. Binds and activates meiotic recombination hot spot ade6-M26.
 
 
 
 0.768
Your Current Organism:
Schizosaccharomyces pombe
NCBI taxonomy Id: 284812
Other names: S. pombe 972h-, Schizosaccharomyces pombe 972h-
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