node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
brx1 | ebp2 | Q9HGL6 | O13802 | Ribosome biogenesis protein brx1; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | Probable rRNA-processing protein ebp2; Required for the processing of the 27S pre-rRNA. | 0.999 |
brx1 | erb1 | Q9HGL6 | O74399 | Ribosome biogenesis protein brx1; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | Ribosome biogenesis protein erb1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | 0.999 |
brx1 | grn1 | Q9HGL6 | O74791 | Ribosome biogenesis protein brx1; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | GTPase grn1; Required for optimal growth. Required for normal processing of ribosomal pre-rRNA. Required for nuclear export of ribosomal protein rpl2501; Belongs to the TRAFAC class YlqF/YawG GTPase family. | 0.992 |
brx1 | has1 | Q9HGL6 | Q09916 | Ribosome biogenesis protein brx1; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | ATP-dependent RNA helicase has1; ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA. | 0.996 |
brx1 | mrt4 | Q9HGL6 | Q9USZ6 | Ribosome biogenesis protein brx1; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. | 0.994 |
brx1 | ppp1 | Q9HGL6 | O60164 | Ribosome biogenesis protein brx1; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | Pescadillo homolog; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | 0.990 |
brx1 | rlp24 | Q9HGL6 | Q10353 | Ribosome biogenesis protein brx1; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | Ribosome biogenesis protein rlp24; Involved in the biogenesis of the 60S ribosomal subunit. Ensures the docking of nog1 to pre-60S particles. Activates and recruits ATPase afg2 to cytoplasmic pre-60S ribosomal particles. | 0.991 |
brx1 | tif6 | Q9HGL6 | O94476 | Ribosome biogenesis protein brx1; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export; Belongs to the eIF-6 family. | 0.966 |
brx1 | wdr74 | Q9HGL6 | O94698 | Ribosome biogenesis protein brx1; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | Ribosome biogenesis protein nsa1; Involved in the biogenesis of the 60S ribosomal subunit. | 0.990 |
brx1 | ytm1 | Q9HGL6 | Q9URY0 | Ribosome biogenesis protein brx1; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | Ribosome biogenesis protein ytm1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | 0.998 |
ebp2 | brx1 | O13802 | Q9HGL6 | Probable rRNA-processing protein ebp2; Required for the processing of the 27S pre-rRNA. | Ribosome biogenesis protein brx1; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | 0.999 |
ebp2 | erb1 | O13802 | O74399 | Probable rRNA-processing protein ebp2; Required for the processing of the 27S pre-rRNA. | Ribosome biogenesis protein erb1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | 0.998 |
ebp2 | grn1 | O13802 | O74791 | Probable rRNA-processing protein ebp2; Required for the processing of the 27S pre-rRNA. | GTPase grn1; Required for optimal growth. Required for normal processing of ribosomal pre-rRNA. Required for nuclear export of ribosomal protein rpl2501; Belongs to the TRAFAC class YlqF/YawG GTPase family. | 0.998 |
ebp2 | has1 | O13802 | Q09916 | Probable rRNA-processing protein ebp2; Required for the processing of the 27S pre-rRNA. | ATP-dependent RNA helicase has1; ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA. | 0.992 |
ebp2 | mrt4 | O13802 | Q9USZ6 | Probable rRNA-processing protein ebp2; Required for the processing of the 27S pre-rRNA. | Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. | 0.996 |
ebp2 | ppp1 | O13802 | O60164 | Probable rRNA-processing protein ebp2; Required for the processing of the 27S pre-rRNA. | Pescadillo homolog; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | 0.998 |
ebp2 | rlp24 | O13802 | Q10353 | Probable rRNA-processing protein ebp2; Required for the processing of the 27S pre-rRNA. | Ribosome biogenesis protein rlp24; Involved in the biogenesis of the 60S ribosomal subunit. Ensures the docking of nog1 to pre-60S particles. Activates and recruits ATPase afg2 to cytoplasmic pre-60S ribosomal particles. | 0.994 |
ebp2 | tif6 | O13802 | O94476 | Probable rRNA-processing protein ebp2; Required for the processing of the 27S pre-rRNA. | Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export; Belongs to the eIF-6 family. | 0.990 |
ebp2 | wdr74 | O13802 | O94698 | Probable rRNA-processing protein ebp2; Required for the processing of the 27S pre-rRNA. | Ribosome biogenesis protein nsa1; Involved in the biogenesis of the 60S ribosomal subunit. | 0.998 |
ebp2 | ytm1 | O13802 | Q9URY0 | Probable rRNA-processing protein ebp2; Required for the processing of the 27S pre-rRNA. | Ribosome biogenesis protein ytm1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | 0.997 |