STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cbf12Transcription factor cbf12; Transcription factor which function may be to trigger the increase of adhesion at stationary phase, possibly by counteracting or replacing cbf11 at the respective promoters. May also play a cbf11- antagonistic role in the regulation of a number of other important processes such as extracellular material production, colony morphogenesis, ploidy maintenance, or meiosis. (963 aa)    
Predicted Functional Partners:
cbf11
Transcription factor cbf11; Transcription factor that behaves as a negative regulator of adhesion. Recognizes specifically the canonical CSL response element GTGA/GGAA. May also play a cbf12-antagonistic role in the regulation of a number of other important processes such as extracellular material production, colony morphogenesis, ploidy maintenance, or meiosis. Belongs to the Su(H) family.
      
 0.905
zfs1
Zinc finger protein zfs1; Binds to specific AU-rich elements (ARE) in the 3'- untranslated region of target mRNAs and promotes their degradation. Binds to ARE present in the arz1 mRNA and stimulates the rate of arz1 mRNA decay. Required for coordination of septum formation with exit from mitosis. Involved in the mating response pathway. Induces sexual development and ascus formation.
   
 
 0.879
SPAC2H10.01
Uncharacterized transcriptional regulatory protein C2H10.01.
   
  
 0.781
ptl1
Probable triacylglycerol lipase C1450.16c; Releases specific fatty acids from neutral lipid triacylglycerols (TAG) thereby supplying fatty acids to a general acylation process.
   
  
 0.763
gsf2
Galactose-specific cell agglutination protein gsf2; Galactose-specific adhesion protein essential for non-sexual flocculation and filamentous growth. Required for adhesion and filamentous growth through recognition of galactose residues on cell surface glycoconjugates. Induces flocculation when overexpressed.
   
 
 0.760
lag1
Sphingosine N-acyltransferase lag1; Component of the ceramide synthase complex required for C26- CoA-dependent ceramide synthesis. Facilitates ER-to-Golgi transport of GPI-anchored proteins (By similarity). Involved in the aging process (By similarity).
   
  
 0.757
gsf1
Uncharacterized transcriptional regulatory protein C15D4.02.
      
 0.746
SPBC530.11c
Uncharacterized transcriptional regulatory protein C530.11c.
   
  
 0.745
pfl3
Putative cell agglutination protein pfl3; May be involved in agglutination during conjugation or other aspects of colony formation (By similarity). Induces flocculation when overexpressed ; Belongs to the mam3/map4 family.
   
  
 0.727
arz1
Armadillo repeat-containing zfs1 target protein 1.
      
 0.721
Your Current Organism:
Schizosaccharomyces pombe
NCBI taxonomy Id: 284812
Other names: S. pombe 972h-, Schizosaccharomyces pombe 972h-
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