STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
msy1Mechanosensitive ion channel protein Msy1; Regulates intracellular calcium levels and cell volume for survival in response to hypo-osmotic shock. Acts as a mechanosensitive calcium channel in response to membrane stretch. The conductance is about 0.25 nanosiemens. Involved in maintaining vacuole integrity and protecting the nuclear envelope upon hypo-osmotic shock. (1011 aa)    
Predicted Functional Partners:
msy2
Mechanosensitive ion channel protein Msy2; Regulates intracellular calcium levels and cell volume for survival in response to hypo-osmotic shock. Involved in maintaining vacuole integrity and protecting the nuclear envelope upon hypo-osmotic shock.
  
 
0.742
nmd3
60S ribosomal export protein nmd3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.
   
    0.568
bcp1
Peroxiredoxin bcp1; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events (By similarity). Acts as a scavenger of H(2)O(2).
   
 
 0.519
SPAC9E9.04
Uncharacterized protein C9E9.04.
   
  
 0.488
mmp2
Mitochondrial inner membrane protease subunit 2; Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space.
  
  
 0.480
mug70
Meiotically up-regulated gene 70 protein; Has a role in meiosis.
   
  
 0.475
osr2
Putative voltage-gated potassium channel subunit beta; Probable accessory potassium channel protein which modulates the activity of the pore-forming alpha subunit.
   
  
 0.475
SPBC800.11
Uncharacterized protein C800.11.
     
 0.474
SPAC1039.06
D-serine dehydratase; Converts specifically D-serine to pyruvate and ammonia. May play a role in D-serine detoxification (By similarity); Belongs to the DSD1 family.
   
  
 0.466
SPAC6F6.13c
Uncharacterized membrane protein C6F6.13c.
      
 0.459
Your Current Organism:
Schizosaccharomyces pombe
NCBI taxonomy Id: 284812
Other names: S. pombe 972h-, Schizosaccharomyces pombe 972h-
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