STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mmi1YTH domain-containing protein mmi1; RNA-binding protein that recognizes and binds N6- methyladenosine (m6A)-containing RNAs, a modification present at internal sites of mRNAs and some non-coding RNAs (By similarity). Required for elemination of certain meiosis-specific mRNAs in an early event following transcription. May bind to the cis-acting region (DSR) of the mRNA, activating the nuclear exosome which may lead to the degradation of the transcript from the 3' region. (488 aa)    
Predicted Functional Partners:
red1
Protein red1; Required for elimination of meiosis-specific mRNAs from mitotic cells. Promotes the destabilization of mRNAs containing a degradation signal sequence called determinant of selective removal (DSR) to prevent ectopic expression of meiotic mRNAs in vegetative cells.
    
 0.999
mei2
Meiosis protein mei2; Crucial for commitment to meiosis but it is not sufficient itself for the commitment. May be a splicing regulator.
    
 0.993
pab2
Polyadenylate-binding protein 2.
   
 0.992
rmn1
Uncharacterized RNA-binding protein C902.04.
   
 0.992
pla1
Poly(A) polymerase pla1; Polymerase that creates the 3'-poly(A) tail of mRNA's. May acquire specificity through interaction with a cleavage and polyadenylation factor (CF I).
   
 0.990
rrp6
Exosome complex exonuclease rrp6; Nuclear-specific catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and cryptic unstable transcripts (CUTs), and of mRNAs with processing defects, thereby limiting or excluding their export t [...]
    
 
 0.974
erh1
Enhancer of rudimentary homolog; May have a role in the cell cycle; Belongs to the E(R) family.
   
 
 0.966
rna15
Uncharacterized RNA-binding protein C644.16.
   
 0.961
rhn1
UPF0400 protein C337.03; Belongs to the UPF0400 (RTT103) family.
     
 0.951
rcd1
Cell differentiation protein rcd1; A differentiation-controlling factor that is essential for the onset of sexual development. Induces ste11 when sexual development is invoked through nitrogen starvation.
   
  0.951
Your Current Organism:
Schizosaccharomyces pombe
NCBI taxonomy Id: 284812
Other names: S. pombe 972h-, Schizosaccharomyces pombe 972h-
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