STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPBPB10D8.05cUncharacterized transporter SPBPB10D8.05c. (379 aa)    
Predicted Functional Partners:
phx1
Homeobox transcription factor phx1; Trnascription factor that regulates the expression of the homocitrate synthase (HCS) lys4.
      
 0.720
SPCC757.05c
Peptidase M20 domain-containing protein C757.05c; Belongs to the peptidase M20A family.
      
 0.497
SPAC23A1.14c
Uncharacterized trans-sulfuration enzyme C23A1.14c.
      
 0.491
sul1
Probable sulfate permease C3H7.02; High affinity uptake of sulfate into the cell; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
      
 0.472
str3
Siderophore iron transporter 3; Involved in the transport of siderophore iron and so has a role in iron homeostasis; Belongs to the major facilitator superfamily.
      
 0.430
ggt1
Glutathione hydrolase 1 heavy chain; Catalyzes the transfer of the gamma-glutamyl moiety of glutathione (GSH) and other gamma-glutamyl compounds to amino acids and peptides. Major GSH-degrading enzyme, catalyzing the hydrolytic release of L-glutamate from GSH.
      
 0.429
fft3
ATP-dependent helicase fft3; DNA helicase that possesses intrinsic ATP-dependent nucleosome-remodeling activity and is required for heterochromatin organization. Required for maintaining a heterochromatin chromatin structure at centromeres and subtelomeres by protecting these regions from euchromatin assembly. Enhances the nucleotide exchange activity of the pim1 guanine nucleotide exchange factor and abolishes histone-H3- mediated RanGAP inhibition. Involved in the construction of the centromeres.
      
 0.424
Your Current Organism:
Schizosaccharomyces pombe
NCBI taxonomy Id: 284812
Other names: S. pombe 972h-, Schizosaccharomyces pombe 972h-
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