STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fex1Fluoride export protein 1; Fluoride channel required for the rapid expulsion of cytoplasmic fluoride; Belongs to the fluoride exporter Fluc/FEX family. (311 aa)    
Predicted Functional Partners:
smp4
Uncharacterized protein PB16A4.07.
      
 0.871
SPAC977.12
Probable L-asparaginase 2; Belongs to the asparaginase 1 family.
   
  
 0.817
rex1
Uncharacterized exonuclease C637.09.
   
 
 0.762
smp1
Uncharacterized protein C25B8.20.
      
 0.760
ash2
Set1 complex component ash2; The Set1 complex specifically methylates 'Lys-4' of histone H3.
   
 
 0.580
swd1
Set1 complex component swd1; The Set1 complex specifically methylates 'Lys-4' of histone H3.
   
 
 0.575
spf1
Set1 complex component spp1; The Set1 complex specifically methylates 'Lys-4' of histone H3.
   
 
 0.554
SPBC30B4.09
Putative uncharacterized protein C30B4.09.
      
 0.549
smp2
Putative uncharacterized protein C13G1.16.
      
 0.549
hhf1
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
   
 
 0.542
Your Current Organism:
Schizosaccharomyces pombe
NCBI taxonomy Id: 284812
Other names: S. pombe 972h-, Schizosaccharomyces pombe 972h-
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.