STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
isp5Sexual differentiation process putative amino-acid permease isp5; Belongs to the amino acid-polyamine-organocation (APC) superfamily. (580 aa)    
Predicted Functional Partners:
SPCPB1C11.03
Uncharacterized transporter PB1C11.03.
   
 
 0.759
SPAC4A8.14
Ribose-phosphate pyrophosphokinase 1; 5-phosphoribose 1-diphosphate synthase involved in nucleotide, histidine, and tryptophan biosynthesis. Active in heteromultimeric complexes with other 5-phosphoribose 1-diphosphate synthases (By similarity); Belongs to the ribose-phosphate pyrophosphokinase family.
     
 0.741
SPAC869.04
Putative formamidase C869.04; Hydrolyzes formamide with the production of ammonia which can be used as a source of nitrogen for growth. May also act on acetamide, propanamide and butanamide (By similarity); Belongs to the acetamidase/formamidase family.
 
  
 0.722
isp6
Sexual differentiation process putative subtilase-type proteinase isp6.
   
 
 0.721
SPCC74.04
Uncharacterized amino-acid permease C74.04.
   
  
 0.667
SPAC922.03
Probable 1-aminocyclopropane-1-carboxylate deaminase; Catalyzes a cyclopropane ring-opening reaction, the irreversible conversion of 1-aminocyclopropane-1-carboxylate (ACC) to ammonia and alpha-ketobutyrate.
   
  
 0.647
trp1
Multifunctional tryptophan biosynthesis protein; Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities.
   
 
 0.642
SPAC11D3.18c
Uncharacterized transporter C11D3.18C.
   
 
 0.636
fnx2
Vacuolar membrane amino acid uptake transporter fnx2; MFS-type transporter involved in vacuolar amino acid uptake. Belongs to the major facilitator superfamily.
   
 
 0.630
put4
Probable proline-specific permease put4; Required for high-affinity proline transport. May be responsible for proline recognition and probably also for proline translocation across the plasma membrane. Also functions as non- specific GABA permease. Can also transport alanine and glycine (By similarity); Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
  
 
0.629
Your Current Organism:
Schizosaccharomyces pombe
NCBI taxonomy Id: 284812
Other names: S. pombe 972h-, Schizosaccharomyces pombe 972h-
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