node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SPAPB1A10.07c | pms1 | Q9HDY3 | P54280 | Membrane protein PB1A10.07c. | DNA mismatch repair protein pms1; This protein is involved in the repair of mismatches in DNA. | 0.884 |
exo1 | mlh1 | P53695 | Q9P7W6 | Exodeoxyribonuclease 1; 5'->3' double-stranded DNA exonuclease that could act in a pathway that corrects mismatched base pairs. | Putative MutL protein homolog 1; This protein is involved in the repair of mismatches in DNA. | 0.998 |
exo1 | msh1 | P53695 | O13921 | Exodeoxyribonuclease 1; 5'->3' double-stranded DNA exonuclease that could act in a pathway that corrects mismatched base pairs. | MutS protein homolog 1; Involved in mitochondrial DNA repair; Belongs to the DNA mismatch repair MutS family. | 0.882 |
exo1 | msh2 | P53695 | O74773 | Exodeoxyribonuclease 1; 5'->3' double-stranded DNA exonuclease that could act in a pathway that corrects mismatched base pairs. | DNA mismatch repair protein msh2; Involved in post-replicative DNA-mismatch repair. Binds to mismatch-containing DNA. Required for correct termination of copy synthesis during mating-type switching. Also required for proper chromosome organization during meiosis. | 0.995 |
exo1 | msh3 | P53695 | P26359 | Exodeoxyribonuclease 1; 5'->3' double-stranded DNA exonuclease that could act in a pathway that corrects mismatched base pairs. | DNA mismatch repair protein msh3; Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with msh2 to form MutS beta, which binds to DNA mismatches thereby initiating DNA repair. Msh3 provides substrate- binding and substrate specificity to the complex. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. Acts mainly to repair insertion-deletion loops (IDLs) from 2 to 13 nucleotides in size, but can also repair base-base and single insertion-deletion mismatches that occur during replication. After mismatch bindi [...] | 0.966 |
exo1 | msh6 | P53695 | O74502 | Exodeoxyribonuclease 1; 5'->3' double-stranded DNA exonuclease that could act in a pathway that corrects mismatched base pairs. | DNA mismatch repair protein msh6; Involved in post-replicative DNA-mismatch repair. Has a role towards base-base mispairs and insertion-deletion loops. | 0.989 |
exo1 | pms1 | P53695 | P54280 | Exodeoxyribonuclease 1; 5'->3' double-stranded DNA exonuclease that could act in a pathway that corrects mismatched base pairs. | DNA mismatch repair protein pms1; This protein is involved in the repair of mismatches in DNA. | 0.987 |
exo1 | rad2 | P53695 | P39750 | Exodeoxyribonuclease 1; 5'->3' double-stranded DNA exonuclease that could act in a pathway that corrects mismatched base pairs. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.902 |
exo1 | rhp14 | P53695 | O59753 | Exodeoxyribonuclease 1; 5'->3' double-stranded DNA exonuclease that could act in a pathway that corrects mismatched base pairs. | DNA repair protein rad14; Involved in nucleotide excision repair (NER). Functional in repair of ultraviolet radiation induced damages and in mitotic mutation avoidance. Binds damaged DNA. Binds specifically to base-base mismatches or small insertion/deletion loops with unpaired nucleotides. Maintains GT repeat stability. Functions as a part of the short-patch excision repair system. | 0.561 |
exo1 | swi10 | P53695 | Q06182 | Exodeoxyribonuclease 1; 5'->3' double-stranded DNA exonuclease that could act in a pathway that corrects mismatched base pairs. | Mating-type switching protein swi10; Involved in termination of copy-synthesis during mating-type switching. Involved in nucleotide excision repair of DNA damaged with UV light, bulky adducts, or cross-linking agents. Along with RAD16 forms an endonuclease that specifically degrades single-stranded DNA; Belongs to the ERCC1/RAD10/SWI10 family. | 0.731 |
mlh1 | exo1 | Q9P7W6 | P53695 | Putative MutL protein homolog 1; This protein is involved in the repair of mismatches in DNA. | Exodeoxyribonuclease 1; 5'->3' double-stranded DNA exonuclease that could act in a pathway that corrects mismatched base pairs. | 0.998 |
mlh1 | msh1 | Q9P7W6 | O13921 | Putative MutL protein homolog 1; This protein is involved in the repair of mismatches in DNA. | MutS protein homolog 1; Involved in mitochondrial DNA repair; Belongs to the DNA mismatch repair MutS family. | 0.975 |
mlh1 | msh2 | Q9P7W6 | O74773 | Putative MutL protein homolog 1; This protein is involved in the repair of mismatches in DNA. | DNA mismatch repair protein msh2; Involved in post-replicative DNA-mismatch repair. Binds to mismatch-containing DNA. Required for correct termination of copy synthesis during mating-type switching. Also required for proper chromosome organization during meiosis. | 0.999 |
mlh1 | msh3 | Q9P7W6 | P26359 | Putative MutL protein homolog 1; This protein is involved in the repair of mismatches in DNA. | DNA mismatch repair protein msh3; Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with msh2 to form MutS beta, which binds to DNA mismatches thereby initiating DNA repair. Msh3 provides substrate- binding and substrate specificity to the complex. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. Acts mainly to repair insertion-deletion loops (IDLs) from 2 to 13 nucleotides in size, but can also repair base-base and single insertion-deletion mismatches that occur during replication. After mismatch bindi [...] | 0.995 |
mlh1 | msh6 | Q9P7W6 | O74502 | Putative MutL protein homolog 1; This protein is involved in the repair of mismatches in DNA. | DNA mismatch repair protein msh6; Involved in post-replicative DNA-mismatch repair. Has a role towards base-base mispairs and insertion-deletion loops. | 0.998 |
mlh1 | pms1 | Q9P7W6 | P54280 | Putative MutL protein homolog 1; This protein is involved in the repair of mismatches in DNA. | DNA mismatch repair protein pms1; This protein is involved in the repair of mismatches in DNA. | 0.999 |
mlh1 | rad2 | Q9P7W6 | P39750 | Putative MutL protein homolog 1; This protein is involved in the repair of mismatches in DNA. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.773 |
mlh1 | rhp14 | Q9P7W6 | O59753 | Putative MutL protein homolog 1; This protein is involved in the repair of mismatches in DNA. | DNA repair protein rad14; Involved in nucleotide excision repair (NER). Functional in repair of ultraviolet radiation induced damages and in mitotic mutation avoidance. Binds damaged DNA. Binds specifically to base-base mismatches or small insertion/deletion loops with unpaired nucleotides. Maintains GT repeat stability. Functions as a part of the short-patch excision repair system. | 0.716 |
mlh1 | swi10 | Q9P7W6 | Q06182 | Putative MutL protein homolog 1; This protein is involved in the repair of mismatches in DNA. | Mating-type switching protein swi10; Involved in termination of copy-synthesis during mating-type switching. Involved in nucleotide excision repair of DNA damaged with UV light, bulky adducts, or cross-linking agents. Along with RAD16 forms an endonuclease that specifically degrades single-stranded DNA; Belongs to the ERCC1/RAD10/SWI10 family. | 0.801 |
msh1 | exo1 | O13921 | P53695 | MutS protein homolog 1; Involved in mitochondrial DNA repair; Belongs to the DNA mismatch repair MutS family. | Exodeoxyribonuclease 1; 5'->3' double-stranded DNA exonuclease that could act in a pathway that corrects mismatched base pairs. | 0.882 |