STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
plb1Lysophospholipase 1; Catalyzes the release of fatty acids from lysophospholipids. Required for survival under high osmolarity, for normal osmotic stress- induced gene expression, and for nutrient-mediated repression of sexual differentiation. (613 aa)    
Predicted Functional Partners:
gde1
Glycerophosphodiester phosphodiesterase gde1; Glycerophosphocholine glycerophosphodiesterase responsible for the hydrolysis of intracellular glycerophosphocholine into glycerol-phosphate and choline.
   
 0.914
ale1
Lysophospholipid acyltransferase; Membrane-bound O-acyltransferase that mediates the incorporation of unsaturated acyl chains into the sn-2 position of phospholipids.
   
 0.903
ptl3
Uncharacterized protein C1A6.05c.
     
  0.900
SPAC513.07
Putative uncharacterized oxidoreductase C513.07.
   
  
 0.751
pho841
Putative inorganic phosphate transporter C1683.01; High-affinity transporter for external inorganic phosphate. Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
   
  
 0.607
ncs1
Calcium-binding protein NCS-1; Negatively regulates sporulation perhaps by controlling Ca(2+)-dependent desensitization of git3.
      
 0.606
sty1
Mitogen-activated protein kinase sty1; Mitogen-activated protein kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment. Controls osmotic regulation of transcription of target genes. Involved in osmoregulation and stress response pathways leading to an efficient start of sexual differentiation. Supports translation initiation and facilitates adaptation to environmental stress in part through reducing eIF2-alpha phosphorylation. Links the cell-cycle G2/M control with changes in the extracellular environment that a [...]
   
  0.537
fhn1
Non-classical export protein 2 homolog; Involved in membrane organization and might act as a sensor of sphingolipids that regulates plasma membrane function. Involved in a novel pathway of export of proteins that lack a cleavable signal sequence; Belongs to the NCE102 family.
      
 0.530
plb2
Probable lysophospholipase C1786.02; Catalyzes the release of fatty acids from lysophospholipids.
  
 
0.509
sck2
Serine/threonine-protein kinase sck2; Protein kinase that is part of growth control pathway which is at least partially redundant with the cAMP pathway.
   
 
 0.500
Your Current Organism:
Schizosaccharomyces pombe
NCBI taxonomy Id: 284812
Other names: S. pombe 972h-, Schizosaccharomyces pombe 972h-
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.