node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
arf6 | chc1 | Q9Y7Z2 | Q10161 | ADP-ribosylation factor 6; GTP-binding protein that functions as a molecular switch for the activation of 'new end take off' (NETO), a process in which the directions of cell growth change from a monopolar manner to a bipolar manner in fission yeast. Involved in supplying membrane to the growing new end; Belongs to the small GTPase superfamily. Arf family. | Probable clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. | 0.503 |
arf6 | lsb5 | Q9Y7Z2 | P87308 | ADP-ribosylation factor 6; GTP-binding protein that functions as a molecular switch for the activation of 'new end take off' (NETO), a process in which the directions of cell growth change from a monopolar manner to a bipolar manner in fission yeast. Involved in supplying membrane to the growing new end; Belongs to the small GTPase superfamily. Arf family. | Protein lsb5; Essential for the organization of the actin cytoskeleton, fluid phase endocytosis and vesicle trafficking; Belongs to the LSB5 family. | 0.554 |
bgl2 | glm1 | O13990 | Q10098 | Glucan 1,3-beta-glucosidase; Glucanases possibly play a role in cell expansion during growth, in cell-cell fusion during mating, and in spore release during sporulation. This enzyme may be involved in beta-glucan degradation and also function biosynthetically as a transglycosylase. | Uncharacterized protein C15F9.01c. | 0.422 |
bgl2 | lsb5 | O13990 | P87308 | Glucan 1,3-beta-glucosidase; Glucanases possibly play a role in cell expansion during growth, in cell-cell fusion during mating, and in spore release during sporulation. This enzyme may be involved in beta-glucan degradation and also function biosynthetically as a transglycosylase. | Protein lsb5; Essential for the organization of the actin cytoskeleton, fluid phase endocytosis and vesicle trafficking; Belongs to the LSB5 family. | 0.605 |
chc1 | arf6 | Q10161 | Q9Y7Z2 | Probable clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. | ADP-ribosylation factor 6; GTP-binding protein that functions as a molecular switch for the activation of 'new end take off' (NETO), a process in which the directions of cell growth change from a monopolar manner to a bipolar manner in fission yeast. Involved in supplying membrane to the growing new end; Belongs to the small GTPase superfamily. Arf family. | 0.503 |
chc1 | end4 | Q10161 | Q9P6L5 | Probable clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. | Endocytosis protein end4; Required for cellular morphogenesis and polarization of the cortical cytoskeleton. Required for establishment of new polarized growth zones where it acts in actin organization. Involved plasma membrane internalization and is essential for fluid-phase endocytosis. Belongs to the SLA2 family. | 0.981 |
chc1 | ent1 | Q10161 | O74423 | Probable clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. | Epsin-1; Binds to membranes enriched in phosphatidylinositol 3,5- bisphosphate (PtdIns(3,5)P2) and phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Required for endocytosis and localization of actin. Belongs to the epsin family. | 0.991 |
chc1 | lsb5 | Q10161 | P87308 | Probable clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. | Protein lsb5; Essential for the organization of the actin cytoskeleton, fluid phase endocytosis and vesicle trafficking; Belongs to the LSB5 family. | 0.717 |
chc1 | shd1 | Q10161 | O13736 | Probable clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. | Actin cytoskeleton-regulatory complex protein sla1; Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization (By similarity). | 0.485 |
end4 | chc1 | Q9P6L5 | Q10161 | Endocytosis protein end4; Required for cellular morphogenesis and polarization of the cortical cytoskeleton. Required for establishment of new polarized growth zones where it acts in actin organization. Involved plasma membrane internalization and is essential for fluid-phase endocytosis. Belongs to the SLA2 family. | Probable clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. | 0.981 |
end4 | ent1 | Q9P6L5 | O74423 | Endocytosis protein end4; Required for cellular morphogenesis and polarization of the cortical cytoskeleton. Required for establishment of new polarized growth zones where it acts in actin organization. Involved plasma membrane internalization and is essential for fluid-phase endocytosis. Belongs to the SLA2 family. | Epsin-1; Binds to membranes enriched in phosphatidylinositol 3,5- bisphosphate (PtdIns(3,5)P2) and phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Required for endocytosis and localization of actin. Belongs to the epsin family. | 0.984 |
end4 | lsb5 | Q9P6L5 | P87308 | Endocytosis protein end4; Required for cellular morphogenesis and polarization of the cortical cytoskeleton. Required for establishment of new polarized growth zones where it acts in actin organization. Involved plasma membrane internalization and is essential for fluid-phase endocytosis. Belongs to the SLA2 family. | Protein lsb5; Essential for the organization of the actin cytoskeleton, fluid phase endocytosis and vesicle trafficking; Belongs to the LSB5 family. | 0.612 |
end4 | shd1 | Q9P6L5 | O13736 | Endocytosis protein end4; Required for cellular morphogenesis and polarization of the cortical cytoskeleton. Required for establishment of new polarized growth zones where it acts in actin organization. Involved plasma membrane internalization and is essential for fluid-phase endocytosis. Belongs to the SLA2 family. | Actin cytoskeleton-regulatory complex protein sla1; Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization (By similarity). | 0.760 |
ent1 | chc1 | O74423 | Q10161 | Epsin-1; Binds to membranes enriched in phosphatidylinositol 3,5- bisphosphate (PtdIns(3,5)P2) and phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Required for endocytosis and localization of actin. Belongs to the epsin family. | Probable clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. | 0.991 |
ent1 | end4 | O74423 | Q9P6L5 | Epsin-1; Binds to membranes enriched in phosphatidylinositol 3,5- bisphosphate (PtdIns(3,5)P2) and phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Required for endocytosis and localization of actin. Belongs to the epsin family. | Endocytosis protein end4; Required for cellular morphogenesis and polarization of the cortical cytoskeleton. Required for establishment of new polarized growth zones where it acts in actin organization. Involved plasma membrane internalization and is essential for fluid-phase endocytosis. Belongs to the SLA2 family. | 0.984 |
ent1 | lsb5 | O74423 | P87308 | Epsin-1; Binds to membranes enriched in phosphatidylinositol 3,5- bisphosphate (PtdIns(3,5)P2) and phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Required for endocytosis and localization of actin. Belongs to the epsin family. | Protein lsb5; Essential for the organization of the actin cytoskeleton, fluid phase endocytosis and vesicle trafficking; Belongs to the LSB5 family. | 0.537 |
ent1 | shd1 | O74423 | O13736 | Epsin-1; Binds to membranes enriched in phosphatidylinositol 3,5- bisphosphate (PtdIns(3,5)P2) and phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Required for endocytosis and localization of actin. Belongs to the epsin family. | Actin cytoskeleton-regulatory complex protein sla1; Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization (By similarity). | 0.521 |
glm1 | bgl2 | Q10098 | O13990 | Uncharacterized protein C15F9.01c. | Glucan 1,3-beta-glucosidase; Glucanases possibly play a role in cell expansion during growth, in cell-cell fusion during mating, and in spore release during sporulation. This enzyme may be involved in beta-glucan degradation and also function biosynthetically as a transglycosylase. | 0.422 |
glm1 | lsb5 | Q10098 | P87308 | Uncharacterized protein C15F9.01c. | Protein lsb5; Essential for the organization of the actin cytoskeleton, fluid phase endocytosis and vesicle trafficking; Belongs to the LSB5 family. | 0.580 |
grx1 | lsb5 | O36032 | P87308 | Glutaredoxin-1; The disulfide bond functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase. In addition, it is also involved in reducing some disulfides in a coupled system with glutathione reductase. Thioltransferase catalyzes cellular thiol-disulfide transhydrogenation reactions. It transfers reducing equivalents to cytosolic protein and nonprotein disulfides (By similarity). | Protein lsb5; Essential for the organization of the actin cytoskeleton, fluid phase endocytosis and vesicle trafficking; Belongs to the LSB5 family. | 0.739 |