STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ste24Probable CAAX prenyl protease 1; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (474 aa)    
Predicted Functional Partners:
rce1
Probable CAAX prenyl protease 2; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase U48 family.
   
 0.999
cpp1
Protein farnesyltransferase subunit beta; Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.
     
 0.969
mam4
Protein-S-isoprenylcysteine O-methyltransferase; Mediates C-terminal methylation of the isoprenylated C- terminal cysteine in M-factor.
   
 0.959
cwp1
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha; Catalyzes the transfer of a farnesyl or geranyl-geranyl moiety from farnesyl or geranyl-geranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. The alpha subunit is thought to participate in a stable complex with the substrate. The beta subunit binds the peptide substrate.
     
 0.956
wbp1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit wbp1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...]
   
 
 0.798
yme1
ATP-dependent zinc metalloprotease YME1 homolog; Putative ATP-dependent protease; In the C-terminal section; belongs to the peptidase M41 family.
   
 
 0.699
trp1
Multifunctional tryptophan biosynthesis protein; Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities.
  
  
 0.679
mge1
GrpE protein homolog, mitochondrial; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of ssc1 to substrate proteins (By similarity).
  
  
 0.644
rpl29
60S ribosomal protein L29; Belongs to the eukaryotic ribosomal protein eL29 family.
      
 0.630
iph1
Putative zinc protease mug138; Has a role in meiosis; Belongs to the peptidase M16 family.
   
  
 0.584
Your Current Organism:
Schizosaccharomyces pombe
NCBI taxonomy Id: 284812
Other names: S. pombe 972h-, Schizosaccharomyces pombe 972h-
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