node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
fig4 | spo20 | Q7Z9H9 | Q10137 | Polyphosphoinositide phosphatase; The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). | Sec14 cytosolic factor; Required for transport of secretory proteins from the Golgi complex. Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes in vitro. Essential for viability and secretion. | 0.619 |
fig4 | stt4 | Q7Z9H9 | Q9USR3 | Polyphosphoinositide phosphatase; The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). | Phosphatidylinositol 4-kinase stt4; Acts on phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol 1,4,5,- trisphosphate. | 0.438 |
gdi1 | sec18 | Q10305 | Q9P7Q4 | Probable secretory pathway GDP dissociation inhibitor 1; Belongs to the Rab GDI family. | Vesicular-fusion protein sec18; Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin (By similarity); Belongs to the AAA ATPase family. | 0.605 |
gdi1 | spo20 | Q10305 | Q10137 | Probable secretory pathway GDP dissociation inhibitor 1; Belongs to the Rab GDI family. | Sec14 cytosolic factor; Required for transport of secretory proteins from the Golgi complex. Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes in vitro. Essential for viability and secretion. | 0.614 |
pfd3 | spo20 | Q10143 | Q10137 | Probable prefoldin subunit 3; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins (By similarity); Belongs to the prefoldin subunit alpha family. | Sec14 cytosolic factor; Required for transport of secretory proteins from the Golgi complex. Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes in vitro. Essential for viability and secretion. | 0.869 |
sec18 | gdi1 | Q9P7Q4 | Q10305 | Vesicular-fusion protein sec18; Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin (By similarity); Belongs to the AAA ATPase family. | Probable secretory pathway GDP dissociation inhibitor 1; Belongs to the Rab GDI family. | 0.605 |
sec18 | spo14 | Q9P7Q4 | Q10659 | Vesicular-fusion protein sec18; Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin (By similarity); Belongs to the AAA ATPase family. | Membrane glycoprotein spo14; Required for the formation of transport vesicles from the ER. This function involves the cytoplasmic domain of the protein, which is thought to interact with the small GTP-binding protein sar1. | 0.479 |
sec18 | spo20 | Q9P7Q4 | Q10137 | Vesicular-fusion protein sec18; Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin (By similarity); Belongs to the AAA ATPase family. | Sec14 cytosolic factor; Required for transport of secretory proteins from the Golgi complex. Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes in vitro. Essential for viability and secretion. | 0.603 |
spo13 | spo14 | C6Y4C9 | Q10659 | Sporulation-specific protein 13; Involved in sporulation. Plays a significant role in modification of the spindle pole body prior to spore formation and is required for initiating forespore membrane formation. | Membrane glycoprotein spo14; Required for the formation of transport vesicles from the ER. This function involves the cytoplasmic domain of the protein, which is thought to interact with the small GTP-binding protein sar1. | 0.744 |
spo13 | spo15 | C6Y4C9 | Q10411 | Sporulation-specific protein 13; Involved in sporulation. Plays a significant role in modification of the spindle pole body prior to spore formation and is required for initiating forespore membrane formation. | Sporulation-specific protein 15; Has a role in the initiation of spore membrane formation. | 0.887 |
spo13 | spo2 | C6Y4C9 | C6Y4C2 | Sporulation-specific protein 13; Involved in sporulation. Plays a significant role in modification of the spindle pole body prior to spore formation and is required for initiating forespore membrane formation. | Sporulation-specific protein 2; Involved in sporulation. Plays a significant role in modification of the spindle pole body prior to spore formation and is required for initiating forespore membrane formation. Assists in the localization of spo13 to the outer surface of the SPB. | 0.922 |
spo13 | spo20 | C6Y4C9 | Q10137 | Sporulation-specific protein 13; Involved in sporulation. Plays a significant role in modification of the spindle pole body prior to spore formation and is required for initiating forespore membrane formation. | Sec14 cytosolic factor; Required for transport of secretory proteins from the Golgi complex. Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes in vitro. Essential for viability and secretion. | 0.756 |
spo13 | spo3 | C6Y4C9 | Q9US08 | Sporulation-specific protein 13; Involved in sporulation. Plays a significant role in modification of the spindle pole body prior to spore formation and is required for initiating forespore membrane formation. | Sporulation-specific protein 3; Has a role in spore morphogenesis. Involved in the assembly of the forespore membrane. | 0.759 |
spo14 | sec18 | Q10659 | Q9P7Q4 | Membrane glycoprotein spo14; Required for the formation of transport vesicles from the ER. This function involves the cytoplasmic domain of the protein, which is thought to interact with the small GTP-binding protein sar1. | Vesicular-fusion protein sec18; Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin (By similarity); Belongs to the AAA ATPase family. | 0.479 |
spo14 | spo13 | Q10659 | C6Y4C9 | Membrane glycoprotein spo14; Required for the formation of transport vesicles from the ER. This function involves the cytoplasmic domain of the protein, which is thought to interact with the small GTP-binding protein sar1. | Sporulation-specific protein 13; Involved in sporulation. Plays a significant role in modification of the spindle pole body prior to spore formation and is required for initiating forespore membrane formation. | 0.744 |
spo14 | spo15 | Q10659 | Q10411 | Membrane glycoprotein spo14; Required for the formation of transport vesicles from the ER. This function involves the cytoplasmic domain of the protein, which is thought to interact with the small GTP-binding protein sar1. | Sporulation-specific protein 15; Has a role in the initiation of spore membrane formation. | 0.760 |
spo14 | spo2 | Q10659 | C6Y4C2 | Membrane glycoprotein spo14; Required for the formation of transport vesicles from the ER. This function involves the cytoplasmic domain of the protein, which is thought to interact with the small GTP-binding protein sar1. | Sporulation-specific protein 2; Involved in sporulation. Plays a significant role in modification of the spindle pole body prior to spore formation and is required for initiating forespore membrane formation. Assists in the localization of spo13 to the outer surface of the SPB. | 0.760 |
spo14 | spo20 | Q10659 | Q10137 | Membrane glycoprotein spo14; Required for the formation of transport vesicles from the ER. This function involves the cytoplasmic domain of the protein, which is thought to interact with the small GTP-binding protein sar1. | Sec14 cytosolic factor; Required for transport of secretory proteins from the Golgi complex. Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes in vitro. Essential for viability and secretion. | 0.838 |
spo14 | spo3 | Q10659 | Q9US08 | Membrane glycoprotein spo14; Required for the formation of transport vesicles from the ER. This function involves the cytoplasmic domain of the protein, which is thought to interact with the small GTP-binding protein sar1. | Sporulation-specific protein 3; Has a role in spore morphogenesis. Involved in the assembly of the forespore membrane. | 0.871 |
spo15 | spo13 | Q10411 | C6Y4C9 | Sporulation-specific protein 15; Has a role in the initiation of spore membrane formation. | Sporulation-specific protein 13; Involved in sporulation. Plays a significant role in modification of the spindle pole body prior to spore formation and is required for initiating forespore membrane formation. | 0.887 |