Diacylglycerol O-acyltransferase 1; Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. Cells defective in triacylglycerol synthesis undergo apoptosis upon entry into the stationary phase. Generation of reactive oxygen species (ROS) is essential to lipoapoptosis. Also has monoacylglycerol acyltransferase (MGAT) activity, catalyzing the acyl- CoA-dependent esterification of monoacylglycerol to diacylglycerol (By similarity).

Phospholipid:diacylglycerol acyltransferase; Triacylglycerol formation by an acyl-CoA independent pathway. The enzyme specifically transfers acyl groups from the sn-2 position of a phospholipid to diacylglycerol, thus forming an sn-1- lysophospholipid. Plays a major role in triacylglycerol formation at log phase. Cells defective in triacylglycerol synthesis undergo apoptosis upon entry into the stationary phase. Generation of reactive oxygen species (ROS) is essential to lipoapoptosis. Belongs to the AB hydrolase superfamily. Lipase family.

Palmitoyl-protein thioesterase-dolichyl pyrophosphate phosphatase fusion 1; Essential protein. Removes thioester-linked fatty acyl groups such as palmitate from modified cysteine residues in proteins or peptides during vacuolar degradation. Required for efficient N- glycosylation. Necessary for maintaining optimal levels of dolichol- linked oligosaccharides; In the N-terminal section; belongs to the palmitoyl-protein thioesterase family.

Nuclear elongation and deformation protein 1; May have a role in the maintenance of the nuclear envelope structure and in minichromosome stability. Belongs to the lipin family.

Probable diacylglycerol pyrophosphate phosphatase 1; Catalyzes the dephosphorylation of diacylglycerol phosphate (DGPP) to phosphatidate (PA) and the subsequent dephosphorylation of PA to diacylglycerol (DAG); Belongs to the PA-phosphatase related phosphoesterase family.

CTP-dependent diacylglycerol kinase 1; CTP-dependent diacylglycerol kinase that catalyzes the phosphorylation of diacylglycerol (DAG) to phosphatidate (PA). Controls phosphatidate levels at the nuclear envelope. Counteracts the activity of ned1. May be involved in vesicle trafficking between the endoplasmic reticulum and the Golgi apparatus (By similarity). Involved in pre-tRNA splicing; Belongs to the DGK1 family.

Probable acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. Catalyzes the insertion of a cis double bond at the delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA. Contributes to the biosynthesis of membrane phospholipids, cholesterol esters and triglycerides.

Endoplasmic reticulum chaperone BiP; Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER. Is required for secretory polypeptide translocation. May physically associate with SEC63 protein in the endoplasmic reticulum and this interaction may be regulated by ATP hydrolysis.