STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bun62UBP9-binding protein bun62; Required for the ubp9 recruitment to septa and cell tips but also for its enzymatic activity at these specific locations. (543 aa)    
Predicted Functional Partners:
ubp9
Probable ubiquitin carboxyl-terminal hydrolase 9; Ubiquitin C-terminal hydrolase involved in regulating actin dynamics and/or endocytosis at cell tips and septa. Belongs to the peptidase C19 family.
   
 
 0.993
bun107
UBP9-binding protein bun107; Required for the ubp9 recruitment to septa and cell tips but also for its enzymatic activity at these specific locations.
   
 
 0.991
ubp11
Ubiquitin carboxyl-terminal hydrolase 11.
    
 
 0.806
gem1
Mitochondrial Rho GTPase 1; Mitochondrial GTPase involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution.
 
  
   0.791
ubp15
Ubiquitin carboxyl-terminal hydrolase 21; Involved in regulating the steady-state levels of proteins including prp4.
   
 
 0.761
sfp47
Ubp4-interactor sfp47; Required for the regulation of activity and recruitment of ubp4 to endosomes.
      
 0.755
otu2
Ubiquitin thioesterase otu2; Hydrolase that can remove conjugated ubiquitin from proteins and may therefore play an important regulatory role at the level of protein turnover by preventing degradation.
   
  
 0.747
ftp105
Ubp5-interacting protein ftp105; Required for the localization of ubp5 to the Golgi apparatus. Involved in detoxification of cadmium ion.
   
  
 0.741
ubp1
Probable ubiquitin carboxyl-terminal hydrolase 1.
    
 
 0.734
ubp7
Probable ubiquitin carboxyl-terminal hydrolase 7.
   
  
 0.730
Your Current Organism:
Schizosaccharomyces pombe
NCBI taxonomy Id: 284812
Other names: S. pombe 972h-, Schizosaccharomyces pombe 972h-
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