STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mpa1Uncharacterized protein PB1E7.11c. (319 aa)    
Predicted Functional Partners:
ppr10
Uncharacterized protein C106.19.
    
 
 0.904
maa1
Aspartate aminotransferase, mitochondrial; Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol (By similarity). Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
      
 0.820
mti3
Probable translation initiation factor, mitochondrial; May be involved in mitochondrial translation initiation. Belongs to the IF-3 family.
   
  
 0.764
ppr6
Pentatricopeptide repeat-containing protein 6, mitochondrial; Mitochondrial RNA-binding protein required for the stability of the atp9 mRNA.
   
  
 0.762
ppr7
Pentatricopeptide repeat-containing protein 7, mitochondrial; Mitochondrial RNA-binding protein required for the stability of the atp6 mRNA.
      
 0.758
trz2
Ribonuclease Z 2, mitochondrial; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. May be involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA. Belongs to the RNase Z family.
   
  
 0.754
pos5
NADH kinase pos5, mitochondrial; Phosphorylates both NADH and NAD(+), with a preference for NADH. Anti-oxidant factor and key source of the cellular reductant NADPH (By similarity).
   
  
 0.744
ppr2
Pentatricopeptide repeat-containing protein 2, mitochondrial; Mitochondrial RNA-binding protein that acts as a general translation factor.
   
  
 0.742
mti2
Translation initiation factor IF-2, mitochondrial; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
      
 0.740
yta12
Mitochondrial respiratory chain complexes assembly protein rca1; Acts as a component of the m-AAA protease complex which is a ATP-dependent metalloprotease mediating degradation of non-assembled mitochondrial inner membrane proteins. The complex is necessary for the assembly of mitochondrial respiratory chain and ATPase complexes. Function both in post-translational assembly and in the turnover of mistranslated or misfolded polypeptides (By similarity); In the C-terminal section; belongs to the peptidase M41 family.
      
 0.736
Your Current Organism:
Schizosaccharomyces pombe
NCBI taxonomy Id: 284812
Other names: S. pombe 972h-, Schizosaccharomyces pombe 972h-
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.