STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cis4Probable zinc transporter cis4; Probable zinc transporter involved in Golgi membrane trafficking through the regulation of zinc homeostasis. (732 aa)    
Predicted Functional Partners:
zrg17
Probable zinc transporter zrg17; Probable transporter involved in the regulation of zinc homeostasis; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
   
 
 0.987
knh4
Uncharacterized serine-rich protein C1E8.05.
    
 
 0.796
apm1
AP-1 complex subunit mu-1; Component of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration (By similarity).
   
  
 0.749
zrt1
Zinc-regulated transporter 1; High-affinity zinc transport protein. Regulates intracellular zinc levels; Belongs to the ZIP transporter (TC 2.A.5) family.
   
 
 0.727
its8
GPI ethanolamine phosphate transferase 1; Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor. Belongs to the PIGG/PIGN/PIGO family. PIGN subfamily.
   
 
 0.693
zhf1
Zinc homeostasis factor 1; Involved in zinc homeostasis, where it plays a role in its accumulation in the endoplasmic reticulum/nucleus. Also has a role in the sequestration of cadmium into the endoplasmic reticulum. Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
  
 
 
0.654
zip3
Uncharacterized zinc transporter P8A3.03.
  
 
 0.653
ccc2
Copper-transporting ATPase ccc2; Probably involved in copper transport and in the regulation of cellular copper level. Retrieves copper from the metallochaperone atx1 and incorporates it into trans-Golgi vesicles (By similarity).
  
  
 0.649
san1
Uncharacterized RING finger protein C2A9.04c.
      
 0.640
zip2
Probable zinc transporter zip2; Probable zinc transporter that may mediate zinc remobilization from the endoplasmic reticulum under zinc limitation. Belongs to the ZIP transporter (TC 2.A.5) family.
   
 
 0.637
Your Current Organism:
Schizosaccharomyces pombe
NCBI taxonomy Id: 284812
Other names: S. pombe 972h-, Schizosaccharomyces pombe 972h-
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