STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hop1Meiosis-specific protein hop1; Constituent of the linear elements (LE) during meiosis, the S.pombe equivalents of synaptonemal complexes. (528 aa)    
Predicted Functional Partners:
rec10
Meiotic recombination protein rec10; Involved primarily in the early steps of meiotic recombination localized to chromosome III.
   
 
 0.949
mek1
Meiosis-specific serine/threonine-protein kinase mek1; Probable protein kinase required for meiotic recombination.
   
 
 0.920
rec25
Meiotic recombination protein rec25; Required for correct meiotic chromosome segregation and recombination.
   
  
 0.903
rec27
Meiotic recombination protein rec27; Required for correct meiotic chromosome segregation and recombination.
   
  
 0.901
red1
Protein red1; Required for elimination of meiosis-specific mRNAs from mitotic cells. Promotes the destabilization of mRNAs containing a degradation signal sequence called determinant of selective removal (DSR) to prevent ectopic expression of meiotic mRNAs in vegetative cells.
   
  
 0.883
mug20
Meiotically up-regulated gene 20 protein.
   
  
 0.877
rec7
Meiotic recombination protein rec7; May be involved primarily in the early steps of meiotic recombination.
   
  
 0.780
rec12
Meiotic recombination protein rec12; Required for formation of the double-strand breaks (DSBs) that initiate meiotic recombination. Required for crossover recombination and chiasmatic segregation of chromosomes during meiosis I. Also involved in the faithful equational segregation of chromosomes during meiosis II.
   
  
 0.766
rec24
Meiotic recombination protein rec24; Required for correct meiotic chromosome segregation and recombination.
   
  
 0.757
rec8
Meiotic recombination protein rec8; Involved primarily in the early steps of meiotic recombination. Required to ensure reductional chromosome segregation. Belongs to the rad21 family.
   
 
 0.646
Your Current Organism:
Schizosaccharomyces pombe
NCBI taxonomy Id: 284812
Other names: S. pombe 972h-, Schizosaccharomyces pombe 972h-
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