STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPCC825.01Uncharacterized ABC transporter ATP-binding protein C825.01. (822 aa)    
Predicted Functional Partners:
rli1
Translation initiation factor rli1; Component of the multifactor complex (MFC) involved in translation initiation. Required for the binding of MFC to the 40S ribosome. Required for the processing and nuclear export of the 60S and 40S ribosomal subunits (By similarity).
   
 
 0.752
elf1
mRNA export factor elf1; Has a direct role in the mRNA export process. Appears to act within the rae1 mediated mRNA export pathway. Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily.
   
 
0.736
tef3
Elongation factor 3; The main role of EF-3 may be to transduce nucleoside triphosphate energy into mechanical energy for translocation during translation. EF-3 stimulates EF-1-alpha-dependent binding of aminoacyl- tRNA to the ribosome.
   
 
0.685
tif52
Eukaryotic translation initiation factor 5B; Plays a role in translation initiation. Translational GTPase that catalyzes the joining of the 40S and 60S subunits to form the 80S initiation complex with the initiator methionine-tRNA in the P-site base paired to the start codon. GTP binding and hydrolysis induces conformational changes in the enzyme that renders it active for productive interactions with the ribosome. The release of the enzyme after formation of the initiation complex is a prerequisite to form elongation-competent ribosomes; Belongs to the TRAFAC class translation factor [...]
   
 
 0.672
mrp7
54S ribosomal protein L27, mitochondrial; Involved in mitochondrial genome encoded proteins translation.
   
 
 0.670
rps3
40S ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family.
   
   0.664
rpl26
60S ribosomal protein L26; Belongs to the universal ribosomal protein uL24 family.
   
 
 0.663
rpl35
60S ribosomal protein L35; Belongs to the universal ribosomal protein uL29 family.
   
 
 0.659
mrpl32
Probable 54S ribosomal protein L32, mitochondrial; Component of the large subunit of mitochondrial ribosome. Belongs to the bacterial ribosomal protein bL32 family.
   
   0.657
mrpl8
54S ribosomal protein L8, mitochondrial; Belongs to the bacterial ribosomal protein bL17 family.
  
   0.649
Your Current Organism:
Schizosaccharomyces pombe
NCBI taxonomy Id: 284812
Other names: S. pombe 972h-, Schizosaccharomyces pombe 972h-
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.