node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
cam2 | cch1 | O14008 | O14234 | Myosin 1 light chain cam2; Plays a role in meiosis and sporulation. | Calcium-channel protein cch1; Voltage-gated, high-affinity calcium channel involved in calcium influx in response to some environmental stresses as well as exposure to mating pheromones. Functions together with yam8 to ensure that adequate levels of Ca(2+) are supplied to pmr1 to sustain secretion and growth. Required for growth in low-calcium environments (By similarity). | 0.948 |
cam2 | cdc31 | O14008 | O74435 | Myosin 1 light chain cam2; Plays a role in meiosis and sporulation. | Cell division control protein 31; Required for the proper coordination between exit from mitosis and the initiation of septation. Has a role in bipolar spindle formation during spindle pole body (SPB) duplication. Required for the localization of sad1 to the SPB. | 0.437 |
cam2 | cnb1 | O14008 | Q9UU93 | Myosin 1 light chain cam2; Plays a role in meiosis and sporulation. | Calcineurin subunit B; Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity (By similarity). | 0.845 |
cam2 | fkh1 | O14008 | O42993 | Myosin 1 light chain cam2; Plays a role in meiosis and sporulation. | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Has an important role in sexual development and serves as the target for rapamycin action; Belongs to the FKBP-type PPIase family. FKBP1 subfamily. | 0.884 |
cam2 | myo1 | O14008 | Q9Y7Z8 | Myosin 1 light chain cam2; Plays a role in meiosis and sporulation. | Myosin-1; Type-I myosin implicated in the organization of the actin cytoskeleton. Required for proper actin cytoskeleton polarization. At the cell cortex, assembles in patch-like structures together with proteins from the actin-polymerizing machinery and promotes actin assembly. Functions as actin nucleation-promoting factor (NPF) for the Arp2/3 complex. Contributes to proper septation by transporting vesicles containing septal material to the division site and is involved in the formation of sterol-rich membrane domains at the cell division site. Required also for mating. | 0.989 |
cam2 | ppb1 | O14008 | Q12705 | Myosin 1 light chain cam2; Plays a role in meiosis and sporulation. | Serine/threonine-protein phosphatase 2B catalytic subunit; Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin. Appears to be involved in cytokinesis, mating, transport, nuclear and spindle pole body positioning, and cell shape; Belongs to the PPP phosphatase family. PP-2B subfamily. | 0.795 |
cam2 | prz1 | O14008 | Q09838 | Myosin 1 light chain cam2; Plays a role in meiosis and sporulation. | Transcriptional regulator prz1; Involved in the regulation of calcium ion homeostasis. Binds to the calcineurin-dependent response element. Transcriptionally regulates pmc1. | 0.794 |
cam2 | vcx1 | O14008 | O59768 | Myosin 1 light chain cam2; Plays a role in meiosis and sporulation. | Vacuolar calcium ion transporter; Has a role in promoting intracellular calcium ion sequestration via the exchange of calcium ions for hydrogen ions across the vacuolar membrane. Involved also in manganese ion homeostasis via its uptake into the vacuole (By similarity); Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. | 0.556 |
cch1 | cam2 | O14234 | O14008 | Calcium-channel protein cch1; Voltage-gated, high-affinity calcium channel involved in calcium influx in response to some environmental stresses as well as exposure to mating pheromones. Functions together with yam8 to ensure that adequate levels of Ca(2+) are supplied to pmr1 to sustain secretion and growth. Required for growth in low-calcium environments (By similarity). | Myosin 1 light chain cam2; Plays a role in meiosis and sporulation. | 0.948 |
cch1 | cdc31 | O14234 | O74435 | Calcium-channel protein cch1; Voltage-gated, high-affinity calcium channel involved in calcium influx in response to some environmental stresses as well as exposure to mating pheromones. Functions together with yam8 to ensure that adequate levels of Ca(2+) are supplied to pmr1 to sustain secretion and growth. Required for growth in low-calcium environments (By similarity). | Cell division control protein 31; Required for the proper coordination between exit from mitosis and the initiation of septation. Has a role in bipolar spindle formation during spindle pole body (SPB) duplication. Required for the localization of sad1 to the SPB. | 0.607 |
cch1 | cnb1 | O14234 | Q9UU93 | Calcium-channel protein cch1; Voltage-gated, high-affinity calcium channel involved in calcium influx in response to some environmental stresses as well as exposure to mating pheromones. Functions together with yam8 to ensure that adequate levels of Ca(2+) are supplied to pmr1 to sustain secretion and growth. Required for growth in low-calcium environments (By similarity). | Calcineurin subunit B; Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity (By similarity). | 0.939 |
cch1 | ppb1 | O14234 | Q12705 | Calcium-channel protein cch1; Voltage-gated, high-affinity calcium channel involved in calcium influx in response to some environmental stresses as well as exposure to mating pheromones. Functions together with yam8 to ensure that adequate levels of Ca(2+) are supplied to pmr1 to sustain secretion and growth. Required for growth in low-calcium environments (By similarity). | Serine/threonine-protein phosphatase 2B catalytic subunit; Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin. Appears to be involved in cytokinesis, mating, transport, nuclear and spindle pole body positioning, and cell shape; Belongs to the PPP phosphatase family. PP-2B subfamily. | 0.583 |
cch1 | prz1 | O14234 | Q09838 | Calcium-channel protein cch1; Voltage-gated, high-affinity calcium channel involved in calcium influx in response to some environmental stresses as well as exposure to mating pheromones. Functions together with yam8 to ensure that adequate levels of Ca(2+) are supplied to pmr1 to sustain secretion and growth. Required for growth in low-calcium environments (By similarity). | Transcriptional regulator prz1; Involved in the regulation of calcium ion homeostasis. Binds to the calcineurin-dependent response element. Transcriptionally regulates pmc1. | 0.843 |
cch1 | vcx1 | O14234 | O59768 | Calcium-channel protein cch1; Voltage-gated, high-affinity calcium channel involved in calcium influx in response to some environmental stresses as well as exposure to mating pheromones. Functions together with yam8 to ensure that adequate levels of Ca(2+) are supplied to pmr1 to sustain secretion and growth. Required for growth in low-calcium environments (By similarity). | Vacuolar calcium ion transporter; Has a role in promoting intracellular calcium ion sequestration via the exchange of calcium ions for hydrogen ions across the vacuolar membrane. Involved also in manganese ion homeostasis via its uptake into the vacuole (By similarity); Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. | 0.778 |
cdc31 | cam2 | O74435 | O14008 | Cell division control protein 31; Required for the proper coordination between exit from mitosis and the initiation of septation. Has a role in bipolar spindle formation during spindle pole body (SPB) duplication. Required for the localization of sad1 to the SPB. | Myosin 1 light chain cam2; Plays a role in meiosis and sporulation. | 0.437 |
cdc31 | cch1 | O74435 | O14234 | Cell division control protein 31; Required for the proper coordination between exit from mitosis and the initiation of septation. Has a role in bipolar spindle formation during spindle pole body (SPB) duplication. Required for the localization of sad1 to the SPB. | Calcium-channel protein cch1; Voltage-gated, high-affinity calcium channel involved in calcium influx in response to some environmental stresses as well as exposure to mating pheromones. Functions together with yam8 to ensure that adequate levels of Ca(2+) are supplied to pmr1 to sustain secretion and growth. Required for growth in low-calcium environments (By similarity). | 0.607 |
cdc31 | cnb1 | O74435 | Q9UU93 | Cell division control protein 31; Required for the proper coordination between exit from mitosis and the initiation of septation. Has a role in bipolar spindle formation during spindle pole body (SPB) duplication. Required for the localization of sad1 to the SPB. | Calcineurin subunit B; Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity (By similarity). | 0.716 |
cdc31 | fkh1 | O74435 | O42993 | Cell division control protein 31; Required for the proper coordination between exit from mitosis and the initiation of septation. Has a role in bipolar spindle formation during spindle pole body (SPB) duplication. Required for the localization of sad1 to the SPB. | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Has an important role in sexual development and serves as the target for rapamycin action; Belongs to the FKBP-type PPIase family. FKBP1 subfamily. | 0.405 |
cdc31 | myo1 | O74435 | Q9Y7Z8 | Cell division control protein 31; Required for the proper coordination between exit from mitosis and the initiation of septation. Has a role in bipolar spindle formation during spindle pole body (SPB) duplication. Required for the localization of sad1 to the SPB. | Myosin-1; Type-I myosin implicated in the organization of the actin cytoskeleton. Required for proper actin cytoskeleton polarization. At the cell cortex, assembles in patch-like structures together with proteins from the actin-polymerizing machinery and promotes actin assembly. Functions as actin nucleation-promoting factor (NPF) for the Arp2/3 complex. Contributes to proper septation by transporting vesicles containing septal material to the division site and is involved in the formation of sterol-rich membrane domains at the cell division site. Required also for mating. | 0.566 |
cnb1 | cam2 | Q9UU93 | O14008 | Calcineurin subunit B; Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity (By similarity). | Myosin 1 light chain cam2; Plays a role in meiosis and sporulation. | 0.845 |